Special issue: Physiology and Systems Biology of the Fungal Cell

On the way toward systems biology of Aspergillus fumigatus infection

“…This emerging research field has demonstrated the most progress for unicellular microorganisms such as Escherichia coli and Saccharomyces cerevisiae. Recently, improvement has also been achieved in systems biology of filamentous fungi of molecular biological and industrial interest, in particular of Aspergillus nidulans (David et al, 2006), A. niger (Andersen et al, 2008), and others (Harris, 2009;Andersen and Nielsen, 2009). The largest reconstruction of a metabolic network reported for a filamentous fungus was presented for the industrial workhorse A. niger comprising 2240 enzymatic reactions (Andersen et al, 2008).…”