Sp706the Prevalence, Severity and Diversity of Gastrointestinal Symptoms in Hemodialysis and Peritoneal Dialysis Patients

Mitrović, Miloš; Majster, Zdenka; Damjanović, Tatjana; Janković, Aleksandar; Bajcetic, Sanja; Popović, Jovan; Đurić, Živka; Đorđević, Tanja; Đurić, Petar; Todorov, V; Dimković, Nada

doi:10.1093/ndt/gfv200.25

Cited by 6 publications

(11 citation statements)

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“…Fourteen out of 24 looked at HD patients, with prevalence ranging from 1.6% to 71.7% . Eight studies looked at PD patients, where prevalence ranged from 14.2% to 90.3% . Constipated dialysis patients were found to have lower HR‐QoL scores,and constipated PD patients were also at greater risk of peritonitis …”

Section: Resultsmentioning

confidence: 99%

“…Interestingly, three studies reported that abdominal pain was more common in those having HD . Three out of four articles reported a higher prevalence of reflux in PD patients, than HD.…”

Section: Resultsmentioning

confidence: 99%

“…2 Eight studies looked at PD patients, where prevalence ranged from 14.2% 17 to 90.3%. 20 Constipated dialysis patients were found to have lower HR-QoL scores, 2 and constipated PD patients were also at greater risk of peritonitis. 24 Symptom prevalence sensitive analysis for studies with Newcastle Ottawa Score >5, and for studies using the GSRS are presented in tables 4 and 5 respectively.…”

Section: All Gi Symptomsmentioning

confidence: 95%

“…Articles reporting on GI symptom prevalence in PD Table 5 The prevalence of gastrointestinal (GI) symptoms in haemodialysis (HD) and peritoneal dialysis (PD) patients, reported across the six studies that used the Gastrointestinal Symptom Rating Scale (GSRS) [11][12][13]20,23,24 GI symptom Prevalence range in HD (%) Articles reporting on GI symptom prevalence in HD…”

Section: Gi Symptommentioning

confidence: 99%

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Gastrointestinal symptoms in patients receiving dialysis: A systematic review

et al. 2018

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Section: Resultsmentioning

confidence: 99%

“…Interestingly, three studies reported that abdominal pain was more common in those having HD . Three out of four articles reported a higher prevalence of reflux in PD patients, than HD.…”

Section: Resultsmentioning

confidence: 99%

Section: All Gi Symptomsmentioning

confidence: 95%

Section: Gi Symptommentioning

confidence: 99%

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Gastrointestinal symptoms in patients receiving dialysis: A systematic review

et al. 2018

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“…In the CKD population, the prevalence of constipation has been most extensively examined among patients with ESRD receiving either peritoneal dialysis (PD) or hemodialysis (HD) treatment. 3,6,[35][36][37][38][39][40] In a recent systematic review of 30 observational studies, Zuvela et al 41 investigated gastrointestinal symptoms in a total of 5161 dialysis (3804 HD and 1507 PD) patients and found that constipation was one of the most common gastrointestinal symptoms, with its prevalence ranging from 1.6% to 71.7% and from 14.2% to 90.3% in HD and PD patients, respectively (Table 3 3,4, [35][36][37][38][39][40][41][42][43][44][45][46][47][48] ). According to a few previous studies comparing the prevalence of constipation between HD and PD patients, constipation has been found to be more prevalent in HD than PD patients.…”

Section: Prevalencementioning

confidence: 99%

Constipation in CKD

Sumida

Yamagata

Kövesdy

2020

Kidney International Reports

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Constipation is one of the most common gastrointestinal disorders among patients with chronic kidney disease (CKD) partly because of their sedentary lifestyle, low fiber and fluid intake, concomitant medications (e.g., phosphate binders), and multiple comorbidities (e.g., diabetes). Although constipation is usually perceived as a benign, often self-limited condition, recent evidence has challenged this most common perception of constipation. The chronic symptoms of constipation negatively affect patients' quality of life and impose a considerable social and economic burden. Furthermore, recent epidemiological studies have revealed that constipation is independently associated with adverse clinical outcomes, such as end-stage renal disease (ESRD), cardiovascular (CV) disease, and mortality, potentially mediated by the alteration of gut microbiota and the increased production of fecal metabolites. Given the importance of the gut in the disposal of uremic toxins and in acid-base and mineral homeostasis with declining kidney function, the presence of constipation in CKD may limit or even preclude these ancillary gastrointestinal roles, potentially contributing to excess morbidity and mortality. With the advent of new drug classes for constipation, some of which showing unique renoprotective properties, the adequate management of constipation in CKD may provide additional therapeutic benefits beyond its conventional defecation control. Nevertheless, the problem of constipation in CKD has long been underrecognized and its management strategies have scarcely been documented. This review outlines the current understanding of the diagnosis, prevalence, etiology, outcome, and treatment of constipation in CKD, and aims to discuss its novel clinical and therapeutic implications.

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Gastrointestinal symptom burden and dietary intake in patients with chronic kidney disease

Meade

Leu

Watson

et al. 2021

Journal of Renal Care

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Background Gastrointestinal (GI) symptoms can present a significant burden to patients with chronic kidney disease (CKD) but the reported prevalence is inconsistent. Objective To examine the GI burden and dietary intake in patients with CKD with or without dialysis. Methods This was a cross‐sectional study of 216 adults, recruited from outpatient and dialysis clinics, with CKD stage 4 or 5 not receiving dialysis (CKD‐ND), or receiving haemodialysis (HD) or peritoneal dialysis (PD). Three questionnaires were administered: the Bristol Stool Form Scale (BSFS); a modified Gastrointestinal Symptom Rating Scale and a short Food Frequency Questionnaire. Outcomes were stool frequency and consistency, GI symptoms and dietary intake. Results Data were collected from 216 patients (mean age, 63 years [95% CI: 61, 65]; 63% males; CKD‐ND: n = 134; HD: n = 67; PD: n = 15). Mean stool frequency for all groups was one bowel action per day (p = .45) and consistency was normal (BSFS type 4, p = .95). Overall GI symptom burden was low but several symptoms occurred at least “most of the time” including “tiredness/lethargy” (54% of participants), “reduced appetite” (29%), “early satiety” (25%) and “change in taste” (15%). Low intakes of fresh fruit, vegetables, whole‐grains and legumes were found. No associations were observed between diet and GI symptoms. Conclusion The overall GI symptom burden was low, but >15% of participants reported several symptoms as occurring most to all of the time. Low intakes of fresh fruit, vegetables, whole‐grains and legumes were observed in all CKD patients.

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Sp706the Prevalence, Severity and Diversity of Gastrointestinal Symptoms in Hemodialysis and Peritoneal Dialysis Patients

Cited by 6 publications

References 0 publications

Gastrointestinal symptoms in patients receiving dialysis: A systematic review

Gastrointestinal symptoms in patients receiving dialysis: A systematic review

Constipation in CKD

Gastrointestinal symptom burden and dietary intake in patients with chronic kidney disease

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