Abstract:A major challenge in diagnostic pathology is to identify sensitive and specific markers for tumor origin. Although PAX8 is the most widely used marker for gynecological tumors, it is not entirely specific, which makes it difficult to determine the origin of some tumors with high confidence. Through mining The Cancer Genome Atlas mRNA expression profile data, we identified SOX17 as a potential specific marker at the mRNA level for gynecological tumors. To test SOX17 expression at the protein level, we performed… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.