Sonographically guided core biopsy in the assessment of thyroid nodules

Harvey, John N.; Parker, David; De, Parijat; Shrimali, R.K.; Otter, Mark I.

doi:10.1002/jcu.20092

Cited by 58 publications

(76 citation statements)

References 21 publications

(14 reference statements)

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“…Sonographically guided thyroid nodule CB has been shown to be accurate, safe, and well tolerated (15,17,19,(26)(27)(28). There are several theoretical reasons why sonographically guided CB might be useful when thyroid nodule FNA is nondiagnostic: CB can provide more tissue than a nondiagnostic FNA and cellular architecture is retained, facilitating accurate histologic diagnosis (26,29,30).…”

Section: Discussionmentioning

confidence: 99%

Ultrasound-Guided Percutaneous Thyroid Nodule Core Biopsy: Clinical Utility in Patients with Prior Nondiagnostic Fine-Needle Aspirate

Samir

Vij

Seale

et al. 2012

Thyroid

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Background: Five percent to 20% of thyroid nodule fine-needle aspiration (FNA) samples are nondiagnostic. The objective of this study was to determine whether a combination of FNA and core biopsy (CFNACB) would yield a higher proportion of diagnostic readings compared with FNA alone in patients with a history of one or more prior nondiagnostic FNA readings. Methods: We conducted a retrospective study of 90 core biopsies (CBs) performed in 82 subjects (55 women and 27 men) between 2006 and 2008 in an outpatient clinic. Results: CFNACB yielded a diagnostic reading in 87%. The diagnostic reading yield of the CB component of CFNACB was significantly superior to the concurrent FNA component, with CB yielding a diagnosis in 77% of cases and FNA yielding a diagnosis in 47% ( p < 0.0001). The combination of CB and FNA had a higher diagnostic reading yield than either alone. In 69 nodules that had only one prior nondiagnostic FNA, CB was diagnostic in 74%, FNA was diagnostic in 52%, CFNACB was diagnostic in 87%, and CB performed significantly better than FNA ( p = 0.0135). In 21 nodules with two or more prior nondiagnostic FNAs, CFNACB and CB were diagnostic in 86%, FNA was diagnostic in 29%, and CB was significantly better than FNA ( p = 0.0005). Clinical, ultrasound, or histopathologic follow-up was available for 81% (73/90) of the CFNACB procedures. No subject with a benign CFNACB reading was diagnosed with thyroid malignancy in the follow-up period (range 4-37 months, mean 18 months), although one subject had minimal increase in nodule size and was awaiting repeat sonography at study conclusion. Conclusion: Thyroid nodule CFNACB is safe and clinically useful in selected patients when a prior FNA reading is nondiagnostic. CFNACB is superior to either CB or FNA alone. CFNACB should be strongly considered as an alternative to surgery in individuals with two prior nondiagnostic FNAs.

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Section: Discussionmentioning

confidence: 99%

Ultrasound-Guided Percutaneous Thyroid Nodule Core Biopsy: Clinical Utility in Patients with Prior Nondiagnostic Fine-Needle Aspirate

Samir

Vij

Seale

et al. 2012

Thyroid

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“…Although a few studies have compared thyroid FNA and CB, [9][10][11][12][13][14][15]28,29 to our knowledge, only 1 study 29 has described the practice of FNA followed by CB in nondiagnostic or suboptimal FNA cases during the same procedure. A few studies have reported higher accuracy with combined FNA/CB than with either procedure alone.…”

Section: Discussionmentioning

confidence: 99%

“…A few studies have reported higher accuracy with combined FNA/CB than with either procedure alone. 10,11,14 Harvey et al 9 reported that patients who underwent CB had a lower surgery rate compared with patients who underwent FNA (11% vs 43%). Mehrotra et al 15 reported better adequacy with CB than with freehand FNA (inadequate rate of 17.6% vs 34.8%) but did not observe any improvement in accuracy by using CB.…”

Section: Discussionmentioning

confidence: 99%

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Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules

Zhang

Ivanovic

Nemcek

et al. 2008

Cancer

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N‐vinylcarbazole (NVC) was polymerized by 13X zeolite alone in melt (65°C) or in toluene (110°C) and a poly(N‐vinylcarbazole) (PNVC)‐13X composite was isolated. Composites of polypyrrole (PPY) and polyaniline(PANI) with 13X zeolite were prepared via polymerization of the respective monomers in the presence of dispersion of 13X zeolite in water (CuCl2 oxidant) and in CHCl3 (FeCl3 oxidant) at an ambient temperature. The composites were characterized by Fourier transform infrared analyses. Scanning electron microscopic analyses of various composites indicated the formation of lumpy aggregates of irregular sizes distinct from the morphology of unmodified 13X zeolite. X‐ray diffraction analysis revealed some typical differences between the various composites, depending upon the nature of the polymer incorporated. Thermogravimetric analyses revealed the stability order as: 13X‐zeolite > polymer‐13X‐zeolite > polymer. PNVC‐13X composite was essentially a nonconductor, while PPY‐13X and PANI‐13X composites showed direct current conductivity in the order of 10−4 S/cm in either system. However, the conductivity of PNVC‐ 13X composite could be improved to 10−5 and 10−6 S/cm by loading PPY and PANI, respectively. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 101: 913–921, 2006

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“…The fine-needle technique is popular because it is low risk and cytology provides diagnostic information about nuclear and cytoplasmic detail that is not available with a core biopsy. 30 The technique for US-guided fine-needle thyroid biopsy involves three steps: puncture of the nodule or goiter, obtaining the sample, and preparation of the slides. With the surgeon performing the biopsy, results from some studies showed that it is technically feasible, 22 increases adequacy and efficacy, especially with the presence of immediate cytopathology assessment, 24,26 and shortens time for diagnosis of thyroid nodules, which has implications for oncological benefit as well.…”

Section: Fnac = Fine-needle Aspiration Cytologymentioning

confidence: 99%

Can We Improve Thyroid Fine-needle Aspiration Cytology Adequacy in a Low-volume Thyroid Center?

Shaaban¹,

Metry²,

Aspinall³

2017

Oncology &Amp; Hematology Review (US)

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I ntroduction: Thyroid cancer is the most common endocrine malignancy, and has shown an increase in incidence in recent decades. Fine-needle aspiration cytology (FNAC) is the mainstay of assessment of thyroid nodules and diagnosis of malignancy. Several reports have suggested that ultrasound (US)-guided FNAC has many advantages over palpation-guided biopsy. . Also, time to diagnostic FNAC was significantly shorter in the SUS-FNAC group: 24.2 ± 4.5 versus 54.9 ± 11.4 days (p=0.01, unpaired t-test). Conclusion: SUS-guided FNAC for thyroid nodules is a safe and simple technique. This study demonstrates that it leads to improved patient care by reducing inadequacy rate and time to diagnosis in a low-volume thyroid center. KeywordsThyroid nodule, surgeon-performed ultrasonography, fine-needle aspiration cytology (FNAC), adequacy Disclosure: Mohamed Shaaban, Mario Metry, and Sebastian Aspinall have no conflicts of interest to declare. No funding was received in the publication of this article. Approval was obtained to carry out this audit, verbal consent was obtained for each fine-needle aspiration procedure.Compliance with Ethics: All procedures were followed in accordance with the responsible committee on human experimentation and with the Helsinki Declaration of 1975 and subsequent revisions.Authorship: All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship of this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval to the version to be published.Open Access: This article is published under the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, adaptation, and reproduction provided the original author(s) and source are given appropriate credit. Thyroid cancer is the most common endocrine malignancy, and has increased in incidence in recent decades.

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Sonographically guided core biopsy in the assessment of thyroid nodules

Abstract: Sonographically guided core biopsy provides an accurate and safe alternative to FNAC in the assessment of thyroid nodules.

Cited by 58 publications

References 21 publications

Ultrasound-Guided Percutaneous Thyroid Nodule Core Biopsy: Clinical Utility in Patients with Prior Nondiagnostic Fine-Needle Aspirate

Ultrasound-Guided Percutaneous Thyroid Nodule Core Biopsy: Clinical Utility in Patients with Prior Nondiagnostic Fine-Needle Aspirate

Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules

Can We Improve Thyroid Fine-needle Aspiration Cytology Adequacy in a Low-volume Thyroid Center?

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