volume 61, issue 12, P1332-1338 2000
DOI: 10.1016/s0198-8859(00)00213-5
View full text
|
|
Share

Abstract: The metalloproteinase (MPase)-mediated pathway of MHC class I processing is a distinct cellular mechanism that generates soluble HLA proteins. It has been implicated in modulation of immune responses induced during transplantation events. It is, therefore, important to define the characteristics of soluble HLA species produced by the MPase pathway. We have previously shown that some mutant peptide-conformed beta(2)-microglobulin (beta(2)m) free heavy chains (HC) with lower affinity for beta(2)m can be released…

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

1
14
0
2

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals