Solitary CNS Metastasis on Initial Presentation of High Grade Serous Carcinoma of the Fallopian Tube

Harl, Felicity; Niemi, Cassandra; Gettle, Lori Mankowski; Weisman, Paul; Rose, Stephen L.

doi:10.1155/2018/6930986

Cited by 2 publications

(4 citation statements)

References 11 publications

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“…1,5,6 In the present study, we found that there were no pediatric or ado- Clinicians have observed atypical and varied symptoms of PFTC. 14 In this study, only 7.02% (4/57) of patients experienced typical Latzko's triad symptoms. Those at advanced stages always presented with abdominal pain and distension.…”

Section: Discussionmentioning

confidence: 49%

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Clinical characteristics of primary Fallopian tube carcinoma: A single‐institution retrospective study of 57 cases

Gao

et al. 2020

Intl J Gynecology & Obste

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Objective To analyze the clinical profile and prognosis of primary Fallopian tube cancer (PFTC) in order to improve earlier diagnosis. Methods In this retrospective study, 57 women with PFTC were assessed from 2006 to 2016. Pathology, clinical index, recurrence, and survival were analyzed. Results Mean age was 57.35 ± 9.01 years, and 73% (19/26) of the patients with early‐stage PFTC (I/II) were aged less than 60 years. Of patients who presented with abnormal vaginal bleeding, 75% (9/12) were at an early stage and their condition was often misdiagnosed as endometrial carcinoma preoperatively. In patients with Stages I/II and Stages III/IV PFTC, 59.09% (13/22) and 96.43% (27/28), respectively, had adnexal masses on color Doppler ultrasonography. The 5‐year overall survival (OS) and disease‐free survival rates were 69.23% and 44.23%, respectively, and univariate analysis showed that tumor stage and residual tumor size significantly affected the two survival rates. Conclusion Primary Fallopian tube cancer is more likely to be misdiagnosed in patients aged less than 60 years or those presenting with vaginal bleeding at the premenopausal stage. Magnetic resonance imaging, cervical smear, and endometrial brush may be helpful for early PFTC diagnosis. Satisfactory cytoreductive surgery is critical because tumor stage and residual tumor size are significantly associated with the OS rate.

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Section: Discussionmentioning

confidence: 49%

“…Clinicians have observed atypical and varied symptoms of PFTC 14 . In this study, only 7.02% (4/57) of patients experienced typical Latzko's triad symptoms.…”

Section: Discussionmentioning

confidence: 51%

Clinical characteristics of primary Fallopian tube carcinoma: A single‐institution retrospective study of 57 cases

Gao

et al. 2020

Intl J Gynecology & Obste

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“…A 50-year-old woman with metastasis of a fallopian tube cancer to the ovary has also been reported [15]. Other uncommon metastatic regions, including the central nervous system (CNS), uterus and diaphragm, have also been reported recently [11,21,32]. The reported metastatic regions of PFTC are summarized in Table 1.…”

Section: Discussionmentioning

confidence: 99%

“…Metastasis of this disease has been reported in recent years. The rare and distant metastasis sites of PFTC include supradiaphragmatic lymph nodes, axillary lymph nodes, brain, vagina, femur and rib, ovary, cervix, lung, spine, colon, skin and diaphragm [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. However, to our knowledge, no mediastinal metastasis of this tumor has been reported yet.…”

Section: Discussionmentioning

confidence: 99%

Anterior mediastinal metastasis of primary fallopian tube adenocarcinoma: a case report

Zhang

Liu

et al. 2020

J Cardiothorac Surg

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Background: Primary fallopian tube carcinoma (PFTC) is a malignant tumor of the female genital tract that mostly presents intraperitoneal dissemination in clinical practice. The incidence of upper anterior mediastinal metastasis in PFTCs is extremely rare. We herein report a rare case of PFTC mediastinal metastasis after radical resection. When anterior mediastinal metastasis of an unknown origin is encountered, the possibility of PFTC should be considered. Case presentation: A 68-year-old female who was previously diagnosed with PFTC after radical resection of a primary tumor in the fallopian tube was admitted to our department with a right anterior mediastinum mass. Radical resection of the mediastinal mass was performed, and poorly differentiated metastatic adenocarcinoma of the fallopian tube was confirmed. There was no recurrence in the 24 months after the curative operation. Conclusion: To our knowledge, no mediastinal metastasis of PFTC has been reported yet. Thus, we presented this rare case indicating the heterogeneity of this malignant disease and to draw attention to the occasional distant metastasis of PFTC in clinical practice.

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Solitary CNS Metastasis on Initial Presentation of High Grade Serous Carcinoma of the Fallopian Tube

Cited by 2 publications

References 11 publications

Clinical characteristics of primary Fallopian tube carcinoma: A single‐institution retrospective study of 57 cases

Clinical characteristics of primary Fallopian tube carcinoma: A single‐institution retrospective study of 57 cases

Anterior mediastinal metastasis of primary fallopian tube adenocarcinoma: a case report

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