1977
DOI: 10.1001/archderm.113.9.1222
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Solar urticaria treatment by inducing tolerance to artificial radiation and natural light

Abstract: Solar urticaria was treated by means of repeated exposures of the skin to fluorescent lamps or natural sunlight. Repeated exposures over a period of hours induce a state of tolerance in the skin so that urticaria fails to develop. The state of tolerance can be maintained with regular daily exposures, and treatment can lead to complete symptomatic relief. Determination of the action spectrum for urticaria is advisable in order to choose the correct fluorescent lamp for treatment.

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Cited by 37 publications
(17 citation statements)
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“…Another therapeutic option would be desensitization, which is indicated only for cold urticaria, (22,23) heat contact urticaria, (24) and solar urticaria. (25) Nonetheless, this induction of tolerance is not long lasting, and daily exposure to the triggering stimulus is necessary. In our study, no patient was submitted to desensitization protocols.…”
Section: ❚ Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Another therapeutic option would be desensitization, which is indicated only for cold urticaria, (22,23) heat contact urticaria, (24) and solar urticaria. (25) Nonetheless, this induction of tolerance is not long lasting, and daily exposure to the triggering stimulus is necessary. In our study, no patient was submitted to desensitization protocols.…”
Section: ❚ Resultsmentioning
confidence: 99%
“…(26) Additionally, two studies have shown that chronic urticaria seriously compromises the quality of life of patients, due to the debilitating symptoms, which can last for years. (23,25) In one of the studies, 59.8% of patients needed ongoing treatment with AH1. (10) A Brazilian review article mentioned that physical weals are skin conditions resulting from the presence of mastocyte with decreased threshold for degranulation, induced by environmental physical triggering factors, whether located or diffuse, classic or atypical, acquired or familial, with or without the participation of IgE, with variable durations, that can worsen with stress and disappear spontaneously.…”
Section: ❚ Resultsmentioning
confidence: 99%
“…Patients with photosensitivity diseases usually avoid sunlight exposure. However, repeated exposures to natural sunlight or action spectrum by artificial light sources may show therapeutic effects (44), when the skin is exposed repeatedly at an interval of a few days. The mechanism by which tolerance is induced may be partially due to the exhaustion of chemical mediators by repeated reactions (21).…”
Section: Treatmentmentioning
confidence: 99%
“…H 1 antihistamines (cetirizine oral solution or loratadinesyrup 2.5–5.0 mg daily) are usually helpful. Tolerance treatment hasbeen advocated in more severely affected patients ( 29, 30 ).…”
Section: Physical Urticariasmentioning
confidence: 99%