Social relationships and cognitive decline: a systematic review and meta-analysis of longitudinal cohort studies

Kuiper, Joël; Zuidersma, Marij; Zuidema, Sytse U.; Burgerhof, Johannes G. M.; Stolk, Ronald; Voshaar, Richard C. Oude; Smidt, Nynke

doi:10.1093/ije/dyw089

Cited by 175 publications

(262 citation statements)

References 106 publications

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“…These results are consistent with some but not other previous research . For instance, Griffin et al found that loneliness correlated with lower cognitive function whereas social isolation was longitudinally associated with worse cognitive performance in older Americans (n = 6654).…”

Section: Discussionsupporting

confidence: 91%

“…Over the past decade, the study of loneliness and social isolation as potential risk factors for cognitive decline has gained increasing attention. Previous studies have suggested that being alone or never married, low frequency of interactions, small social network size, or negative experiences of social support predict steeper cognitive decline . Moreover, a recent meta‐analysis of longitudinal population‐based studies found evidence that loneliness is also associated with an increased risk of dementia …”

Section: Introductionmentioning

confidence: 99%

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Are loneliness and social isolation associated with cognitive decline?

Lara

Caballero

Rico-Uribe

et al. 2019

Int J Geriat Psychiatry

250

169

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Objective This study aimed to examine the association of loneliness and social isolation on cognition over a 3‐year follow‐up period in middle‐ and older‐aged adults. Methods Data from a Spanish nationally representative sample were analyzed (n = 1691; aged 50 years or older). Loneliness, social isolation, and cognition (immediate recall, delayed recall, verbal fluency, forward digit span, backward digit span, and a composite cognitive score) were assessed both at baseline and at follow‐up. Adjusted generalized estimating equations models were performed. Results Loneliness was significantly associated with lower scores in the composite cognitive score, immediate and delayed recall, verbal fluency, and backward digit span (B = −0.14 to B = −3.16; P < .05) and with a more rapid decline from baseline to follow‐up in two out of six cognitive tests. Higher social isolation was associated with lower scores in the composite cognitive score, verbal fluency, and forward digit span (B = −0.06 to B = −0.85; P < .05). The effect of loneliness and social isolation on cognition remained significant after the exclusion of individuals with depression. Conclusions Both loneliness and social isolation are associated with decreased cognitive function over a 3‐year follow‐up period. The development of interventions that include the enhancement of social participation and the maintenance of emotionally supportive relationships might contribute to cognitive decline prevention and risk reduction.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Are loneliness and social isolation associated with cognitive decline?

Lara

Caballero

Rico-Uribe

et al. 2019

Int J Geriat Psychiatry

250

169

View full text Add to dashboard Cite

show abstract

“…Thus, identification and management of frailty and cognitive impairment are essential for enhancing health in later years. In addition, in accordance with previous studies, the present findings show a beneficial effect of social contact in terms of people's cognition . Participants who were in more frequent contact with their child showed a smaller percentage of cognitive decline compared with those with infrequent contact.…”

Section: Discussionsupporting

confidence: 93%

Association of solidarity between adult children and older parents with cognitive decline

Kim

Chon

2018

Geriatrics Gerontology Int

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“…Tracking cross-level interactions among networks may also offer new approaches for therapeutic intervention and manipulation. For example, a recent meta-analysis suggested a possible association between aspects of social relationships and cognitive decline 132 . Mechanisms of brain networks and social networks become intertwined (Fig.…”

Section: Current Frontiersmentioning

confidence: 99%

Network neuroscience

2017

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Despite substantial recent progress, our understanding of the principles and mechanisms underlying complex brain function and cognition remains incomplete. Network neuroscience proposes to tackle these enduring challenges. Approaching brain structure and function from an explicitly integrative perspective, network neuroscience pursues new ways to map, record, analyze and model the elements and interactions of neurobiological systems. Two parallel trends drive the approach: the availability of new empirical tools to create comprehensive maps and record dynamic patterns among molecules, neurons, brain areas and social systems; and the theoretical framework and computational tools of modern network science. The convergence of empirical and computational advances opens new frontiers of scientific inquiry, including network dynamics, manipulation and control of brain networks, and integration of network processes across spatiotemporal domains. We review emerging trends in network neuroscience and attempt to chart a path toward a better understanding of the brain as a multiscale networked system.

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Social relationships and cognitive decline: a systematic review and meta-analysis of longitudinal cohort studies

Cited by 175 publications

References 106 publications

Are loneliness and social isolation associated with cognitive decline?

Are loneliness and social isolation associated with cognitive decline?

Association of solidarity between adult children and older parents with cognitive decline

Network neuroscience

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