Social media discussions provide new insight about perceptions of hydroxyurea in the sickle cell community

Walker, Aisha L.; Gaydos, Laura M.; Farzan, Rosta; Castro, Laura De; Jonassaint, Charles R.

doi:10.1002/ajh.25430

Cited by 3 publications

(2 citation statements)

References 6 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These networks may play an influential role in their consideration of curative treatments. 26 Raising a child with SCD is associated with a myriad of psychological stressors for primary caregivers. 27 Families experience stress from the burden of SCD treatments, such as CTT, regular clinic visits, and the financial hardship from missed workdays.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Primary caregiver decision‐making in hematopoietic cell transplantation and gene therapy for sickle cell disease

Sinha

Bakshi

Ross

et al. 2020

Pediatric Blood & Cancer

View full text Add to dashboard Cite

Background: Improved outcomes and the availability of clinical trials of hematopoietic cell transplantation (HCT) from alternate donors and genetically modified autologous hematopoietic progenitor cells have expanded the applicability of HCT for sickle cell disease (SCD). To understand the perspective of primary caregivers exploring HCT in the current milieu, we asked the research question "What motivates primary caregivers to decide to consider HCT and to seek, and to attend, an HCT consultation?" Procedures: We conducted qualitative interviews with primary caregivers within one week after a consultation for HCT for SCD. Data were analyzed using open and axial coding stages of grounded theory methodology. Results: We interviewed 29 primary caregivers (26 females, age 29 to 64 [median 42] years). Primary caregivers report of SCD complications in their child included at least one in the last year by 23 (82%), few or none by 8 (28%), and pain on ≥3 days a week by 13 (46%) primary caregivers. Qualitative analysis revealed that primary caregivers, (i) learn about curative options through social networks, social media, and the news media; (ii) seek consultation because of their child's diminished quality of life, recent complications, an imminent major medical decision, or anxiety about future severe complications; and (iii) see gene therapy as a new, less invasive, and more acceptable treatment. Conclusion: Primary caregivers of children with SCD learn about HCT through social networks, social and news media, and explore HCT as a means to prevent SCD complications and help their child live a normal life.

show abstract

Section: Discussionmentioning

confidence: 99%

“…With the increase in the number of successful HCT for SCD, it is likely that families will come across, on social networks, more individuals with a positive experience of HCT. These networks may play an influential role in their consideration of curative treatments 26 …”

Section: Discussionmentioning

confidence: 99%