Social Implications of Childhood Crohn's Disease

Moody, G. A.; Eaden, Jayne; Mayberry, J. F.

doi:10.1097/00005176-199904001-00008

Cited by 78 publications

(41 citation statements)

References 12 publications

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“…According to parent reports, adolescents with IBD have more emotional, social, and thought problems and lower competence than their healthy peers [35] . The disease disturbs adolescents' quality of life [25,36,37] , may have negative consequences for education and school functioning [38,39] , and may be a cause of difficulties in employment, such as finding or maintaining a desired job [40][41][42] . Furthermore, adolescents with severe IBD have disturbed sleep and are overtired tion to even minor cognitive problems that may be aggravated during the growth process [43,52,53] .…”

Section: Psychological Symptoms In Ibdmentioning

confidence: 99%

Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease

Filipović¹,

Filipović²

2014

WJG

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Ulcerative colitis and Crohn's disease, commonly known as inflammatory bowel disease (IBD), draw attention from specialists of various disorders, including gastroenterology, psychiatry, and radiology. The involvement of a cortical influence in the brain-gut axis as well as the interaction of the hypothalamic-pituitary-adrenal axis and the peripheral nervous system provide an initial explanation of the psychological symptoms associated with IBD. The involvement of structures the limbic system, such as the anterior cingulate cortex, the prefrontal cortex, and the amygdala, paves the way for the discovery of the mechanisms underlying depression depression, anxiety, alexithymia, personality traits, and other psychological impairments following the onset of IBD. Psychiatric therapy in IBD patients is almost as important as the gastroenterological approach and consists of pharmacological treatment and psychotherapy. Neither of the available psychiatric treatment methods is considered the golden standard because both methods have side effects, and psychotropic medication can provoke the worsening of IBD symptoms. Thus, both approaches must be applied with awareness of the possibility of side effects. We suggest that psychiatrists and gastroenterologists work together to reach a consensus on IBD therapy to ensure success and to reduce side effects and relapse to the lowest possible rates.© 2014 Baishideng Publishing Group Co., Limited. All rights reserved.Key words: Inflammatory bowel disease; Psychiatry; Treatment; Personality traits; Depression; Anxiety Core tip: The involvement of a dysfunction of brain-gut interactions in the pathogenesis of inflammatory bowel disease (IBD) is represented by a dysfunction of the autonomic nervous system, an abnormal hypothalamicpituitary-adrenal axis and cholinergic anti-inflammatory pathway, a deleterious effect of stress and depression, an abnormal coupling of the prefrontal cortex-amygdaloid complex, and an abnormal relation between the microbiota and the brain as pro-inflammatory factors. New investigations have provided a critical link between forebrain changes and abdominal pain independent of active disease and drug treatment, providing a potential basis for an explanation of the psychological symptoms and brain influence in the pathogenesis of IBD.

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Section: Psychological Symptoms In Ibdmentioning

confidence: 99%

Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease

Filipović¹,

Filipović²

2014

WJG

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“…Therapy also allows patients to discuss coping strategies, disease related themes, and close family relationships, and to deal with difficult questions that arise; for example 64% of pediatric patients with IBD wonder "Why me?" [44,58]. Many of the above studies have found long lasting effects from brief therapeutic interventions which may contribute to reduced health care utilization and costs and decreased productivity loss in managing IBD, for example reduction of outpatient attendances, sick-leave and hospital days [6,20,31,47,51,55,58].…”

Section: Discussionmentioning

confidence: 99%

“…This is disappointing considering that psychological interventions may not only help IBD patients with depressive and anxious symptoms or psychiatric co morbidity, they may also reduce stress (perception) and thereby decrease number of flare ups or prolong remission [26]. Additionally, in children with IBD, feelings of underachievement due to their illness (80%), inability to play with friends (50%), play sports (67%), leave the house (60%), lack of support from teacher (50%), and school absences (60%) may contribute to children's QoL and can be addressed during psychosocial therapeutic interventions [44]. This would possibly increase school functioning, which has been shown to have significant deficits in children with IBD both during active disease and remission compared to controls [34].…”

Section: Psychological Interventionsmentioning

confidence: 99%

"Role of Psychosocial Factors on the Course of Inflammatory Bowel Disease and Associated Psychotherapeutic Approaches. A Fresh Perspective and Review"

Banan¹

2015

GHOA

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In this review article we seek to provide a fresh prospective on the role of psychosocial factors such as stress, anxiety, and depression, in the course of Inflammatory Bowel Diseases (IBD). IBD patients suffer from depression and anxiety at higher rates than the general population. Psychological stressors adversely affect the course of IBD through activation and possible dysfunction of the Brain-Gut-Axis. The mechanisms by which psychological factors increase mucosal inflammation, disrupt the intestinal barrier, and thereby worsen IBD symptoms are not well understood. This is a new and upcoming area of research that needs more attention because of its importance in managing and treating patients with IBD while also reducing costs associated with these disorders. Therefore, in this article we also seek to explore treatment options that target these psychological factors. Interventions include both pharmacological and nonpharmacological psychotherapeutic approaches. Whereas some of these therapies improve IBD symptoms, many also improve depression, anxiety, stress symptoms, fatigue, relapse rate, and Quality of Life (QOL) in both adults and children with IBD. These psychological factors are important determinants of health related quality of life (HRQOL) and therefore are important symptoms to treat alongside the IBD symptoms.

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“…3 Some disease-related factors have been found to be associated with poor emotional functioning, including pain, 4 elevated stress levels, 5 and impairments in physical functioning. 6,7 In fact, nearly half of children and adolescents with IBD report functional limitations in daily activities due to IBD, such as missing school or social events. 6 Given the associations between psychosocial stressors and physical functioning, 8 it is possible that improving psychosocial functioning can have a positive effect on physical outcomes, such as pain.…”

mentioning

confidence: 99%

“…6,7 In fact, nearly half of children and adolescents with IBD report functional limitations in daily activities due to IBD, such as missing school or social events. 6 Given the associations between psychosocial stressors and physical functioning, 8 it is possible that improving psychosocial functioning can have a positive effect on physical outcomes, such as pain.…”

mentioning

confidence: 99%