Social egg freezing: risk, benefits and other considerations

Petropanagos, Angel; Cattapan, Alana; Βaylis, Françoise; Leader, Arthur

doi:10.1503/cmaj.141605

Cited by 90 publications

(65 citation statements)

References 13 publications

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“…Total costs range from $9000 to $17 000 per cycle (private insurance may cover $3000-$8000 medication costs) with an additional $300-$500 annual storage fee. 3 Additional costs are incurred when patients return to use the frozen eggs to cover the thawing, fertilization and subsequent embryo transfer(s).…”

Section: Fees For This Elective Treatment Are Not Covered By Governmementioning

confidence: 99%

Elective egg freezing for age-related fertility decline

Gale

Clancy

Claman

2020

CMAJ

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Section: Fees For This Elective Treatment Are Not Covered By Governmementioning

confidence: 99%

Elective egg freezing for age-related fertility decline

Gale

Clancy

Claman

2020

CMAJ

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“…4 The use of autologous oocytes cryopreserved at an early age for social reasons has recently become very popular, allowing women to delay motherhood due to personal, professional, financial, and psychological factors, without renouncing the possibility of using their own oocytes and thus maintaining a low risk of chromosomal abnormalities, which are known to increase with age. 100 Currently available results are still scarce, as few patients have actually returned to use their stored oocytes. 101 To date, the largest study involved 1,468 women undergoing elective oocyte cryopreservation for nononcologic reasons, of whom the vast majority (94.2%) were motivated by age-related issues.…”

Section: Indications and Outcomes Spermatozoamentioning

confidence: 99%

Perspectives in Gamete and Embryo Cryopreservation

Rienzi¹,

Iussig²,

Dovere³

et al. 2018

Semin Reprod Med

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Cryopreserved gametes and embryos are a major feature of human-assisted reproduction and patient care services, accounting for an increasing number of births worldwide. Since the first success obtained using frozen human spermatozoa, cryopreservation technology has been successfully extended to include oocytes and embryos, in a variety of both medical and nonmedical indications. Over the years, the available procedures have become widely implemented and the increasing evidence of its efficacy has contributed to acceptance of the technology. Nevertheless, a gold standard protocol that would be universally shared by clinics has yet to be definitively established and, therefore, research into cryopreservation of gametes and embryos cannot be considered concluded. Moreover, much effort should be committed to the definition and resolution of safety issues, the establishment of automation, and investigations about the potentiality of immature germ cells or stem cells.

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“…This information should be provided to all women who inquire about social egg freezing, regardless of sexual orientation, age, disability, health, relationship, or socioeconomic status. Family physicians should frame discussions about this practice within the broader context of reproductive health and family-planning to assist women in making informed choices [ 67 ].…”

Section: Concerns Of Both Medical and Social Naturementioning

confidence: 99%

Postponing Pregnancy Through Oocyte Cryopreservation for Social Reasons: Considerations Regarding Clinical Practice and the Socio-Psychological and Bioethical Issues Involved

Simopoulou

Sfakianoudis²,

Bakas

et al. 2018

Medicina

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Oocyte freezing for ‘social reasons’ refers to women of reproductive age who are aiming to prolong, protect and secure their fertility. The term emerged to describe application of the highly promising technique, namely vitrification on oocytes retrieved through controlled ovarian stimulation (COS) from women intending to preserve their fertility for social reasons. These women opt to cryopreserve their oocytes at a point in their life when they need to postpone childbearing on the grounds of so called ‘social’ reasons. These reasons may include a highly driven career, absence of an adequate partner, financial instability, or personal reasons that make them feel unprepared for motherhood. This is a sensitive and multifaceted issue that entails medical, bioethical and socio-psychological components. The latest trend and the apparent increase noted on oocyte freezing for ‘social reasons’ has prompted our team of fertility specialists, embryologists, obstetricians, gynecologists and psychologists to proceed with a thorough, critical and all-inclusive comprehensive analysis. The wide range of findings of this analysis involve concerns of embryology and epigenetics that shape decisions made in the IVF laboratory, issues regarding obstetric and perinatal concerns on the pregnancy concluding from these oocytes and the respective delivery management and neonatal data, to the social and bioethical impact of this trend’s application. This literature review refers to matters rising from the moment the ‘idea’ of this option is ‘birthed’ in a woman’s thoughts, to proceeding and executing it clinically, up until the point of the pediatric follow up of the children born. We aim to shed light to the controversial issue of oocyte freezing, while objectively exhibit all aspects regarding this complex matter, as well as to respectfully approach how could the prospect of our future expectations be shaped from the impact of its application.

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Social egg freezing: risk, benefits and other considerations

Cited by 90 publications

References 13 publications

Elective egg freezing for age-related fertility decline

Elective egg freezing for age-related fertility decline

Perspectives in Gamete and Embryo Cryopreservation

Postponing Pregnancy Through Oocyte Cryopreservation for Social Reasons: Considerations Regarding Clinical Practice and the Socio-Psychological and Bioethical Issues Involved

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