Social and behavioural determinants of syphilis: Modelling based on repeated cross-sectional surveys from 2010 and 2017 among 278,256 men who have sex with men in 31 European countries

Sexually transmitted infections and clinical features in monkeypox (mpox) patients in Madrid, Spain

“…The mpox patient profile with the highest number of STI was HIV-positive MSM despite good control of illness (TCD4 lymphocytes >200 and HIV viral load undetectable). Previous syphilis infection (n = 22/30) was also frequent in mpox patients although syphilis infection is the most frequently STI in MSM population and mpox patients [ 7 , 8 ]. More than 50% out of 187 mpox patients screened for IgG syphilis at HULP had a positive IgG serology.…”

Epidemiology and determinants of reemerging bacterial sexually transmitted infections (STIs) and emerging STIs in Europe

“… 39 The surveys identified factors associated with syphilis diagnosis, including living with HIV, having more frequent condomless anal intercourse with non-steady male partners, recent STI-screening, selling sex, and PrEP use. 54 The same data also suggested that changes in testing-practices and/or frequency likely played a larger role in reported increases in gonorrhoea and chlamydia than did changes in behaviour.…”

“…For example, core groups with both a high STI prevalence and a high number of multiple inter-connected partners are believed to be particularly relevant for explaining increases of syphilis. 54 , 82 Conversely these core groups are thought to be much less important in the overall increase in cases of CT and NG. 83 Moreover, the role of networks in the transmission of Monkeypox virus (MPXV) during the early phase of the outbreak in Belgium has been recently described.…”

Genetic Profiling of the Full-Length tprK Gene in Patients with Primary and Secondary Syphilis

“…Syphilis, which is caused by the spirochete Treponema pallidum , is a chronic sexually transmitted infection ( 1 , 2 ). Its explosive resurgence in many countries, particularly among men who have sex with men (MSM) and persons living with HIV, has sounded alarm bells ( 3 , 4 ). The persistence of the pathogen for the lifetime of an infected individual is the greatest threat to the patient's quality of life ( 5 ); however, the mechanism underlying persistent infection is not fully understood.…”