SNOT‐22 in a Control Population

Erskine, Sally; Philpott, Carl

doi:10.1177/0194599814541627a312

Cited by 10 publications

(14 citation statements)

References 4 publications

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“…Twenty‐two items are covered and scored on a Likert grading system (0‐5). The resulting scores range from 0 to 110, and the median score in a normal population without CRS ranges between 6.5 and 7 in published studies …”

Section: Methodsmentioning

confidence: 99%

“…The resulting scores range from 0 to 110, and the median score in a normal population without CRS ranges between 6.5 and 7 in published studies. 3,8,15 The SF-12 questionnaire (a condensed version of the SF-36) is a The EQ-5D-5L is a standardised measure of health status consisting of a visual analogue scale (VAS) to assess patient-reported health state on the day of completing the survey (0=worst imaginable health state and 100=best imaginable health state) in addition to a questionnaire with five dimensions (mobility, self-care, usual activities, pain/discomfort and anxiety/depression) (EuroQol 2011). 16 Each of the dimensions asks for a response that corresponds to a health status level of no problems, slight problems, moderate problems, severe problems and extreme problems that are coded level 1-5, respectively.…”

Section: Methodsmentioning

confidence: 99%

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Health utility reporting in chronic rhinosinusitis patients

Bewick

Morris

Hopkins

et al. 2017

Clinical Otolaryngology

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Objectives: Direct comparison of different diseases allows clinicians and researchers to place the burden of symptoms and impact on quality of life of each condition in context. Generic health-related quality-of-life assessment tools allow such analysis, and limited data are available for British patients with chronic rhinosinusitis.Design: As part of a larger feasibility study, patients underwent baseline assessment using the SNOT-22, SF-12 and EQ-5D-5L tools. Data were analysed using Microsoft Excel and algorithms available for the analysis of the later two tools. We plotted EQ-5D-5L VAS and utility scores and SF-12 MCS and PCS scores separately against SNOT-22 scores and quantified associations using bivariate ordinary least squares regression analysis.Setting: Patients were prospectively recruited from six UK outpatient clinics. Participants: Adult patients with chronic rhinosinusitis without nasal polyps (CRSsNPs).Main Outcome measures: Baseline SNOT-22, SF-12 and EQ-5D-5L scores.Results: Fifty-two adults were recruited with a mean age of 55 years, 51% were male. The mean SNOT-22 score was 43.82. Mental and physical component scores of the SF-12 were 46.53 and 46, respectively. Mean index score computed form the EQ-5D-5L was 0.75. Worse (higher) SNOT-22 scores were associated with lower EQ-5D-5L VAS and utility scores and SF-12 MCS and PCS scores. Conclusion:The EQ-5D-5L suggests that British CRSsNPs patients are negatively impacted with regards to quality of life. We found the SF-12 to be less sensitive and conclude that the EQ-5D-5L tool is a quick and accessible method for assessing QOL in order it can be compared with other disease states.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Health utility reporting in chronic rhinosinusitis patients

Bewick

Morris

Hopkins

et al. 2017

Clinical Otolaryngology

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“…Although we did not explicitly identify CRS in our patient population, our findings indicate that worse SNOT‐22 scores correlated with worsened pulmonary health in CF patients. Other studies have demonstrated that patients without sinonasal pathology have an average SNOT‐22 score of 12.0 . Among our study population, baseline patients had an average SNOT‐22 score of 25.4, whereas exacerbation patients had an average score of 38.4.…”

Section: Discussionmentioning

confidence: 68%

Sinonasal quality‐of‐life declines in cystic fibrosis patients with pulmonary exacerbations

Safi

DiMango

Keating

et al. 2019

Int Forum Allergy Rhinol

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Background In cystic fibrosis (CF), the relationship between chronic rhinosinusitis (CRS) and pulmonary disease is poorly understood. The purpose of this study was to evaluate the relationship between scores on the 22‐item Sino‐Nasal Outcome Test (SNOT‐22) and CF Questionnaire―revised for adolescents and adults over 14 (CFQ‐R 14+), and pulmonary function tests in 2 cohorts of CF patients: those at their baseline health and those with a pulmonary exacerbation. Methods Patients >18 years old seen in a Cystic Fibrosis Foundation‒accredited clinic completed the SNOT‐22 and CFQ‐R 14+ instruments. Patients presenting for routine care represented the baseline cohort. Patients diagnosed with a pulmonary exacerbation represented the exacerbation cohort. Average SNOT‐22 and CFQ‐R 14+ scores for both groups were compared using a 2‐sample t test, and correlation coefficient was calculated. Results One hundred three patients were enrolled over 3 months (30 exacerbations and 73 baseline). Patients’ mean age was 32 years (56% female and 44% male). Average SNOT‐22 and CFQ‐R 14+ scores were significantly worse for exacerbation patients (p = 0.001 and p = 0.0003, respectively). Percent predicted forced expiratory volume in 1 second and forced vital capacity were both higher for baseline patients (p = 0.002 and p = 0.001, respectively). Average SNOT‐22 score for all patients was worse than the average score for non‐CF, non‐CRS patients. Conclusion CF patients with pulmonary exacerbations have worse SNOT‐22 and CFQ‐R 14+ scores than CF patients at their baseline health. This finding suggests a temporal relationship between sinonasal and pulmonary quality of life, and that worsening of both is associated with reduced pulmonary function.

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“…All control subjects were students from the university affiliated with the hospital (University College London) and underwent a full clinical evaluation which required a normal clinical history, normal nasal endoscopy (NE) evaluation, negative allergy tests and a SNOT 22 score of less than 10 30 to exclude AR, CRS, DNS, or any other sinonasal disease.…”

Section: Methodsmentioning

confidence: 99%

“…A patient's clinical diagnosis was based on the clinical history, nasendoscopic (NE) evaluation, computerized tomography (CT) findings, allergy tests along with SNOT‐22 scores (a score of more than 10) 30,31 . Skin prick tests were used to diagnose allergic rhinitis as per the British Society of Allergy and Clinical Immunology guidelines 32 …”

Section: Methodsmentioning

confidence: 99%

Diagnosing nasal obstruction and its common causes using the nasal acoustic device: A pilot study

Kaura

Tan

et al. 2020

Laryngoscope Investig Oto

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Objectives: There is a need to develop a medical device which can accurately measure normal and abnormal nasal breathing which the patient can better understand in addition to being able to diagnose the cause for their nasal obstruction. The aim is to evaluate the accuracy of the nasal acoustic device (NAD) in diagnosing the common causes for nasal obstruction and diagnosing normal and abnormal (nasal obstruction) nasal breathing. Methods: This pilot study recruited 27 patients with allergic rhinitis (AR), chronic rhinosinusitis (CRS), and a deviated nasal septum (DNS) which represents the common causes for NO and 26 controls (with normal nasal breathing). Nasal breathing sounds were recorded by the NAD akin to two small stethoscopes placed over the left and right nasal ala. The novel outcome metrics for the NAD include inspiratory nasal acoustic score (INA) score, expiratory nasal acoustic (ENA) score and the inspiratory nasal obstruction balance index (NOBI). The change in acoustic score following decongestant is key in this diagnostic process. Results: Pre-decongestant ENA score was used to detect the presence of nasal obstruction in patients compared to controls, with a sensitivity of 0.81 (95% CI: 0.66-0.96) and a specificity of 0.77 (0.54-1.00). Post-decongestant percentage change in INA score was used to identify the presence of AR or CRS, with a sensitivity of 0.87 (0.69-1.00) and specificity of 0.72 (0.55-0.89) for AR; and a sensitivity of 0.92 (0.75-1.00) and specificity of 0.69 (0.52-0.86) for CRS. Post-decongestant inspiratory NOBI was used to identify DNS, with a sensitivity of 0.77 (0.59-0.95) and specificity of 0.94 (0.82-1.00).

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SNOT‐22 in a Control Population

Cited by 10 publications

References 4 publications

Health utility reporting in chronic rhinosinusitis patients

Health utility reporting in chronic rhinosinusitis patients

Sinonasal quality‐of‐life declines in cystic fibrosis patients with pulmonary exacerbations

Diagnosing nasal obstruction and its common causes using the nasal acoustic device: A pilot study

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