2020
DOI: 10.1364/ol.393213
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Snapshot multispectral endomicroscopy

Abstract: Multispectral endomicroscopy provides tissue functional information in addition to structural information for accurate disease diagnosis. In this Letter, we propose a snapshot multispectral endomicroscope that employs a fiber bundle to deliver an in-body tissue spatial–spectral datastream to an external compressive spectral imager. Equipped with an end-to-end deep-learning-based reconstruction algorithm, we are able to capture tissue multispectral data in video rates and reconstruct high-resolution multispectr… Show more

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Cited by 74 publications
(29 citation statements)
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“…With this simple change and keeping the network structure, significant improvement has been achieved on both simulation and real data. Our proposed method can also be used in other spectral imaging systems [28,29] as well as other snapshot compressive systems such as video [5,30], spectral-temporal [4], spatialtemporal [6] imaging.…”
Section: Discussionmentioning
confidence: 99%
“…With this simple change and keeping the network structure, significant improvement has been achieved on both simulation and real data. Our proposed method can also be used in other spectral imaging systems [28,29] as well as other snapshot compressive systems such as video [5,30], spectral-temporal [4], spatialtemporal [6] imaging.…”
Section: Discussionmentioning
confidence: 99%
“…Beyond automatic diagnosis and super‐resolution approaches in IVM, recent advances also highlight ways in which DL can enable novel instrumentation development and image reconstructions to enable new functionalities for compact microscopy systems. Such examples include multispectral endomicroscopy [129], more robust mosaicking for FOV expansion [130], and end‐to‐end image reconstruction using disordered fiber‐optic probes [131,132]. We anticipate that similarly to ex vivo microscopy, in the coming years DL will be increasingly utilized to overcome physical constraints, augment contrast mechanisms, and enable new capabilities for IVM systems.…”
Section: Applications In Biomedical Opticsmentioning
confidence: 99%
“…Equipped with rich spectral information, hyperspectral imaging has wide applications in agriculture, food detection, mineral detection and medical imaging [82].…”
Section: Hyperspectral Imagingmentioning
confidence: 99%
“…Use deep learning to decode the high-dimensional data from multiple encoded measurements [192] [193] Propose a deep neural network based on a standard tensor ADMM algorithm [175] Build a video CI system using a digital micro-mirror device and develop end-to-end convolutional neural networks for reconstruction [176] Build a multispectral endomicroscopy CI system using coded aperture plus disperser and develop end-to-end convolutional neural networks for reconstruction [82] Propose a new auto-focus mechanisms based on reinforcement learning [195] AI optimizes structure and design of CI system Assist in designing the physical layout of imaging system for compact imaging [201] Perform end-to-end optimization of an optical system [48] [88] [202]- [205] Introduce special optical elements, or replace the original ones for lightweight system [206]- [209] Show better results by novel end-to-end network frameworks via optimization [191] [210]- [213] AI promotes scene adaptive CI system…”
Section: Ai Improves Quality and Efficiency Of CI Systemmentioning
confidence: 99%