Small Choroidal Melanoma

Choroidal Neovascularization Induced by Transcleral Microdiathermy for Localization of a Juxtapapillary Choroidal Melanoma

“…Failure to accurately localize juxtapapillary melanomas may, in part, be attributable to their poor tumor control rates. 2,3 Post-equatorial and amelanotic tumors do not transilluminate well by conventional transpupillary transillumination.…”

Choroidal Neovascularization Induced by Transcleral Microdiathermy for Localization of a Juxtapapillary Choroidal Melanoma

“…Failure to accurately localize juxtapapillary melanomas may, in part, be attributable to their poor tumor control rates. 2,3 Post-equatorial and amelanotic tumors do not transilluminate well by conventional transpupillary transillumination.…”

Treating Some Small Melanocytic Choroidal Lesions Without Waiting for Growth

“…1 Accompanying that issue was an editorial that delineated the pros and cons to observation vs early treatment for small choroidal melanoma. 2 In that editorial, an argument was made for a randomized clinical trial to definitively address the critical clinical question, "Do I treat now or do I wait?" Now approaching the latter half of a decade from this discussion, we as the ophthalmologists managing patients with suspected small choroidal melanomas are still faced with the dilemma as to the best treatment approach for these patients.…”

“…1 Regarding colon cancer, colonoscopy with early removal of precancerous polyps is associated with improved prognosis. 2 The prognosis for cutaneous mela-noma has improved in the last 50 years, also because of early detection and removal of precancerous lesions. 3 From an ophthalmic standpoint, we have achieved improved prognosis for several ocular malignancies over the past few decades, including retinoblastoma, 4 orbital rhabdomyosarcoma, 5,6 and eyelid sebaceous carcinoma.…”

A Prediction Model to Discriminate Small Choroidal Melanoma from Choroidal Nevus

“…Controversy regarding management of small choroidal melanoma stems from the diagnostic uncertainty [1-4]. The majority of tumors labeled as small choroidal melanoma (5.0–16.0 mm in largest basal diameter and 1.0 mm–2.5 mm in height) within the Collaborative Ocular Melanoma Study (COMS) observation arm remained stable during observation with clinical behavior compatible with a diagnosis of choroidal nevus rather than a melanoma [5, 6]. As the tumors within the small size criteria may include nevi and melanoma, these small choroidal melanocytic tumors are best referred to as indeterminate choroidal melanocytic tumor (IMT) emphasizing the need to differentiate choroidal nevus from melanoma [7, 8].…”

Choroidal Neovascularization Induced by Transcleral Microdiathermy for Localization of a Juxtapapillary Choroidal Melanoma

“…Failure to accurately localize juxtapapillary melanomas may, in part, be attributable to their poor tumor control rates. 2,3 Post-equatorial and amelanotic tumors do not transilluminate well by conventional transpupillary transillumination.…”

Treating Some Small Melanocytic Choroidal Lesions Without Waiting for Growth

“…1 Accompanying that issue was an editorial that delineated the pros and cons to observation vs early treatment for small choroidal melanoma. 2 In that editorial, an argument was made for a randomized clinical trial to definitively address the critical clinical question, "Do I treat now or do I wait?" Now approaching the latter half of a decade from this discussion, we as the ophthalmologists managing patients with suspected small choroidal melanomas are still faced with the dilemma as to the best treatment approach for these patients.…”

“…1 Regarding colon cancer, colonoscopy with early removal of precancerous polyps is associated with improved prognosis. 2 The prognosis for cutaneous mela-noma has improved in the last 50 years, also because of early detection and removal of precancerous lesions. 3 From an ophthalmic standpoint, we have achieved improved prognosis for several ocular malignancies over the past few decades, including retinoblastoma, 4 orbital rhabdomyosarcoma, 5,6 and eyelid sebaceous carcinoma.…”

A Prediction Model to Discriminate Small Choroidal Melanoma from Choroidal Nevus

“…Controversy regarding management of small choroidal melanoma stems from the diagnostic uncertainty [1-4]. The majority of tumors labeled as small choroidal melanoma (5.0–16.0 mm in largest basal diameter and 1.0 mm–2.5 mm in height) within the Collaborative Ocular Melanoma Study (COMS) observation arm remained stable during observation with clinical behavior compatible with a diagnosis of choroidal nevus rather than a melanoma [5, 6]. As the tumors within the small size criteria may include nevi and melanoma, these small choroidal melanocytic tumors are best referred to as indeterminate choroidal melanocytic tumor (IMT) emphasizing the need to differentiate choroidal nevus from melanoma [7, 8].…”

Choroidal Neovascularization Induced by Transcleral Microdiathermy for Localization of a Juxtapapillary Choroidal Melanoma

“…Failure to accurately localize juxtapapillary melanomas may, in part, be attributable to their poor tumor control rates. 2,3 Post-equatorial and amelanotic tumors do not transilluminate well by conventional transpupillary transillumination.…”

Treating Some Small Melanocytic Choroidal Lesions Without Waiting for Growth

“…1 Accompanying that issue was an editorial that delineated the pros and cons to observation vs early treatment for small choroidal melanoma. 2 In that editorial, an argument was made for a randomized clinical trial to definitively address the critical clinical question, "Do I treat now or do I wait?" Now approaching the latter half of a decade from this discussion, we as the ophthalmologists managing patients with suspected small choroidal melanomas are still faced with the dilemma as to the best treatment approach for these patients.…”

“…1 Regarding colon cancer, colonoscopy with early removal of precancerous polyps is associated with improved prognosis. 2 The prognosis for cutaneous mela-noma has improved in the last 50 years, also because of early detection and removal of precancerous lesions. 3 From an ophthalmic standpoint, we have achieved improved prognosis for several ocular malignancies over the past few decades, including retinoblastoma, 4 orbital rhabdomyosarcoma, 5,6 and eyelid sebaceous carcinoma.…”

A Prediction Model to Discriminate Small Choroidal Melanoma from Choroidal Nevus

“…Controversy regarding management of small choroidal melanoma stems from the diagnostic uncertainty [1-4]. The majority of tumors labeled as small choroidal melanoma (5.0–16.0 mm in largest basal diameter and 1.0 mm–2.5 mm in height) within the Collaborative Ocular Melanoma Study (COMS) observation arm remained stable during observation with clinical behavior compatible with a diagnosis of choroidal nevus rather than a melanoma [5, 6]. As the tumors within the small size criteria may include nevi and melanoma, these small choroidal melanocytic tumors are best referred to as indeterminate choroidal melanocytic tumor (IMT) emphasizing the need to differentiate choroidal nevus from melanoma [7, 8].…”