Sleep and Daytime Behavior in Children With Obstructive Sleep Apnea and Behavioral Sleep Disorders

Owens, Judith; Opipari, Lisa C.; Nobile, Chantelle; Spirito, Anthony

doi:10.1542/peds.102.5.1178

Cited by 213 publications

(128 citation statements)

References 26 publications

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“…In typically developing children, sleep disruption may lead to daytime sleepiness and may manifest itself as hyperactivity, inattention, or aggression. 22 Thus, sleep disorders can have wide ranging implications for daytime functioning, developmental progress, and quality of life for both the child and his family. Effective intervention can have a positive impact on educational and developmental progress, as well as community life opportunities.…”

Section: Sleep Disordersmentioning

confidence: 99%

“…In addition, these guidelines also raise awareness of the association of GI disorders with self-injurious behavior and sleep disturbances, and the frequent atypical presentation of GI dysfunction in individuals with ASD. 22,24 Although some ASD persons present with symptoms that are easily recognized by most healthcare providers, many others may not. As previously noted, atypical behaviors may include chest tapping, facial grimacing, and intermittent gulping, chewing on nonedible objects, including shirts and sleeves, constant eating or drinking, seeking of abdominal pressure, aggressions, and selfinjurious behaviors to name just a few.…”

Section: Gastrointestinal Disordersmentioning

confidence: 99%

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Medical Comorbidities in Autism: Challenges to Diagnosis and Treatment

2010

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Summary:Ever since its original description by Leo Kanner in l943, autism has been generally defined by its clinical characteristics and core symptoms that include impaired social skills, isolated areas of interest, and delayed and disordered language. Over time, it has become apparent that autism is a heterogeneous disorder with regard to its clinical presentation, etiology, underlying neurobiology, and degree of severity. As a result, the termed diagnosis of autism spectrum disorders (ASDs) has come into common usage. With advancements in clinical care, there has come the appreciation that many ASD children, adolescents, and adults may have medically relevant disorders that may negatively impact their developmental progress and behavior, but which frequently go undetected. Many of these medical conditions are treatable, often resulting in improved developmental gains and quality of life for the patient and family. In addition, the possibility exists that some of these medical conditions may suggest the presence of important genetic and/or biologic markers, which, if identified, can refine our ability to be more precise in categorizing clinical and genetic subtypes within the autism spectrum.

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Section: Sleep Disordersmentioning

confidence: 99%

Section: Gastrointestinal Disordersmentioning

confidence: 99%

Medical Comorbidities in Autism: Challenges to Diagnosis and Treatment

2010

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“…(12) In addition, respiratory events associated with sleep disorders, in childhood and adolescence, are associated with greater frequency of disorders related to learning, behavior and attention. (13,14) In patients with AR, quality of life is often impaired not only due to the typical symptoms of the disease-sneezing, pruritus, nasal obstruction and rhinorrhea-but also due to the activity of the mediators that participate in its pathophysiology and can disrupt sleep. (15) Among the most commonly implicated mediators are histamine, leukotrienes (C4 and D4), interleukins (IL-1β, IL-4, IL-5 and IL-13), prostaglandin D2, substance P and bradykinin.…”

Section: Impact On Sleepmentioning

confidence: 99%

Rinite alérgica: indicadores de qualidade de vida

Camelo-Nunes

Solé

2010

J. bras. pneumol.

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The objective of this review was to present evidence of the relationship between allergic rhinitis and impairment of quality of life. The data sources were original articles, reviews and consensus statements entered into the Medline and LILACS databases between 1997 and 2008. The following search terms were used: "allergic rhinitis"; "quality of life"; and "sleep disorders". Quality of life is often impaired in patients with allergic rhinitis, due to the classic symptoms of the disease (sneezing, pruritus, rhinorrhea and nasal obstruction). In addition, the pathophysiology of allergic rhinitis often disrupts sleep, leading to fatigue, irritability, memory deficits, daytime sleepiness and depression. The total burden of this disease goes beyond impairment of physical and social functioning. It has also a financial impact, which becomes greater when we consider the evidence that allergic rhinitis is a possible causal factor of comorbidities, such as asthma and sinusitis. Nasal obstruction, the most prominent symptom, is associated with sleep disorders, which can have a profound effect on mental health, learning, behavior and attention. Finally, allergic rhinitis-a chronic condition that affects adults, adolescents and children-is often underdiagnosed or inadequately treated. The deleterious impact that allergic rhinitis-related sleep disorders have on patient capacity to perform activities of daily living is an important component of the morbidity of the disease. With an accurate diagnosis, there are various available treatments that can reduce the burden of allergic rhinitis.Keywords: Rhinitis, allergic, perennial; Rhinitis, allergic, seasonal; Quality of life; Sleep disorders. ResumoO objetivo desta revisão foi apresentar evidências da relação entre rinite alérgica e redução da qualidade de vida. As fontes de dados foram artigos originais, revisões e consensos indexados nos bancos de dados Medline e LILACS entre 1997 e 2008. As palavras de busca foram "rinite alérgica", "qualidade de vida" e "distúrbios do sono". Os pacientes com rinite alérgica frequentemente têm redução na qualidade de vida causada pelos sintomas clássicos da doença (espirros, prurido, coriza e obstrução). Além disso, a fisiopatologia da rinite alérgica, com frequência, interrompe o sono, ocasionando fadiga, irritabilidade, déficits de memória, sonolência diurna e depressão. A carga total da doença recai não apenas no funcionamento social e físico prejudicados, mas também no impacto financeiro, que se torna maior quando se consideram as evidências de que a rinite alérgica é um possível fator casual de comorbidades, tais como a asma e a sinusite. A obstrução nasal, o mais proeminente dos sintomas, está associada a eventos respiratórios relacionados aos distúrbios do sono, uma condição que tem profundo efeito sobre a saúde mental, o aprendizado, o comportamento e a atenção. Finalmente, a rinite alérgica -doença crônica que afeta crianças, adolescentes e adultos -frequentemente é subdiagnosticada ou inadequadamente tratada. O impacto dele...

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“…14 Intermittent nocturnal hypoxia accompanied by frequent arousals from sleep (documented by electroencephalography) results in sleep fragmentation. 15 The neurobehavioral consequence of this sequence is altered behavior in children.…”

Section: Historymentioning

confidence: 99%