Maria Yurchenko, Astrid Skjesol, Liv Ryan, Gabriel Mary Richard, Richard Kumaran Kandasamy, Ninghai Wang, Cox Terhorst, Harald Husebye, Terje Espevik
Abstract:Yurchenko et al. discover that the Ig-like receptor molecule SLAMF1 enhances production of type I interferon induced by Gram-negative bacteria through modulation of MyD88-independent TLR4 signaling. This makes SLAMF1 a potential target for controlling inflammatory responses against Gram-negative bacteria.
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