Skin preparation for preventing infection following caesarean section

Abstract

Little evidence is available from the included randomised controlled trials to evaluate different agent forms, concentrations and methods of skin preparation for preventing infection following caesarean section. Therefore, it is not yet clear what sort of skin preparation may be most efficient for preventing postcaesarean wound and surgical site infection. There is a need for high-quality, properly designed randomised controlled trials with larger sample sizes in this field. High priority questions include comparing types of antiseptic (especially iodine versus chlorhexidine), the timing and duration of applying the antiseptic (especially previous night versus day of surgery, and application methods (scrubbing, swabbing and draping).

Povidone‐iodine ointment demonstrates in vitro efficacy against biofilm formation

“…Chlorhexidine gluconate is a widely used antiseptic and has previously been compared to PVP-I in prevention of infection following a caesarean section, where it was associated with lower rates of bacterial growth after 18 hours (45). In our study, chlorhexidine gluconate again displayed efficacy against both biofilms over both time points.…”

Povidone‐iodine ointment demonstrates in vitro efficacy against biofilm formation

“…Chlorhexidine gluconate is a widely used antiseptic and has previously been compared to PVP-I in prevention of infection following a caesarean section, where it was associated with lower rates of bacterial growth after 18 hours (45). In our study, chlorhexidine gluconate again displayed efficacy against both biofilms over both time points.…”

Antiseptic Skin Preparation for Preventing Surgical Site Infection at Caesarean Section

“…Of the five trials included none compared chlorhexidine alcohol with povidone iodine. The reviewers concluded that "little evidence was available from the included randomised controlled trials to evaluate different agent forms, concentrations and methods of skin preparation for preventing infection following caesarean section" [3]. Most of the cases of SSI were of the superficial type which was similar to findings of other investigators [13] [16].…”

“…A Cochrane review of skin preparation for preventing infection following caesarean section [3] found no significant difference in the incidence of SSI between skin antiseptics used in the six trials included in the review. Of the five trials included none compared chlorhexidine alcohol with povidone iodine.…”

Post-Caesarean Group B Streptococcal Pelviperitonitis: A Case Report

“…These germs are, for the most part, usual saprophytes of the vagina. It is during a multiplication of these germs due to an ill-adapted Toin appropriate antibiotic therapy, corticosteroids, the trauma of childbirth, or the introduction of other germs during obstetric maneuvers that an infection develops [5].…”

Povidone‐iodine ointment demonstrates in vitro efficacy against biofilm formation

“…Chlorhexidine gluconate is a widely used antiseptic and has previously been compared to PVP-I in prevention of infection following a caesarean section, where it was associated with lower rates of bacterial growth after 18 hours (45). In our study, chlorhexidine gluconate again displayed efficacy against both biofilms over both time points.…”

Antiseptic Skin Preparation for Preventing Surgical Site Infection at Caesarean Section

“…Of the five trials included none compared chlorhexidine alcohol with povidone iodine. The reviewers concluded that "little evidence was available from the included randomised controlled trials to evaluate different agent forms, concentrations and methods of skin preparation for preventing infection following caesarean section" [3]. Most of the cases of SSI were of the superficial type which was similar to findings of other investigators [13] [16].…”

“…A Cochrane review of skin preparation for preventing infection following caesarean section [3] found no significant difference in the incidence of SSI between skin antiseptics used in the six trials included in the review. Of the five trials included none compared chlorhexidine alcohol with povidone iodine.…”

Post-Caesarean Group B Streptococcal Pelviperitonitis: A Case Report

“…These germs are, for the most part, usual saprophytes of the vagina. It is during a multiplication of these germs due to an ill-adapted Toin appropriate antibiotic therapy, corticosteroids, the trauma of childbirth, or the introduction of other germs during obstetric maneuvers that an infection develops [5].…”

Povidone‐iodine ointment demonstrates in vitro efficacy against biofilm formation

“…Chlorhexidine gluconate is a widely used antiseptic and has previously been compared to PVP-I in prevention of infection following a caesarean section, where it was associated with lower rates of bacterial growth after 18 hours (45). In our study, chlorhexidine gluconate again displayed efficacy against both biofilms over both time points.…”

Antiseptic Skin Preparation for Preventing Surgical Site Infection at Caesarean Section

“…Of the five trials included none compared chlorhexidine alcohol with povidone iodine. The reviewers concluded that "little evidence was available from the included randomised controlled trials to evaluate different agent forms, concentrations and methods of skin preparation for preventing infection following caesarean section" [3]. Most of the cases of SSI were of the superficial type which was similar to findings of other investigators [13] [16].…”

“…A Cochrane review of skin preparation for preventing infection following caesarean section [3] found no significant difference in the incidence of SSI between skin antiseptics used in the six trials included in the review. Of the five trials included none compared chlorhexidine alcohol with povidone iodine.…”

Post-Caesarean Group B Streptococcal Pelviperitonitis: A Case Report

“…These germs are, for the most part, usual saprophytes of the vagina. It is during a multiplication of these germs due to an ill-adapted Toin appropriate antibiotic therapy, corticosteroids, the trauma of childbirth, or the introduction of other germs during obstetric maneuvers that an infection develops [5].…”