“…The limited literature [2][3][4][5][6][7][8] shows that LC usually appears later in the course of the disease, after the symptoms of fatigue, night sweats, weight loss, easy bruising, heapatosplenomegaly and enlarged lymph nodes. Solitary skin lesions manifesting as papules, plaques, nodules, tumours, more rarely as vesicobullous lesions, erythoderma or paronychia may mimic other, benign skin disorders [1,8]. Current treatment options for CLL are based on purine nucleoside analogues (PNAs) (fludarabine, cladribine, pentostatin) administered in combination with cyclophosphamide.…”