Skin cancer healthcare impact: A nation-wide assessment of an administrative database

Duarte, Ana Filipa; Sousa‐Pinto, Bernardo; Delgado, Luís; Costa‐Pereira, Altamiro; Correia, Osvaldo

doi:10.1016/j.canep.2018.08.004

Cited by 20 publications

(21 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Skin cancer is more common among the white races and has undergone a dramatic increase during the last 40 years, due to social changes with regard to exposure to sunlight and UV radiation (UVR) (Weinstock, 2008) [1]. As a result, UVR has come to be regarded as the most important environmental carcinogen, and has driven the health-care sector on a quest for better information and management regarding the effects of solar radiation (Duarte et al, 2018) [5]. The UV spectrum can be divided into three wavelength ranges, UVA (320-400 nm), UVB (280-320) and UVC (200-280 nm).…”

Section: Resultsmentioning

confidence: 99%

“…Its annual increase has been estimated at between 50 and 200% over the last three decades, and these figures continue to increase due to aging populations in the developed world (Waldman and Schmults, 2019) [4]. Although the rate of hospitalization due to melanoma is higher, the incidence of NMSC makes health care costs higher for this type of skin cancer in absolute terms (Duarte et al 2018) [5]. Exposure to sunlight, pale skin, and immunosupression are risk factors for NMSC.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chemopreventive effect of pomegranate and cocoa extracts on ultraviolet radiation-induced photocarcinogenesis in SKH-1 mice

Gómez-García¹,

López²,

Sánchez³

et al. 2020

PLoS ONE

View full text Add to dashboard Cite

Non-melanoma skin cancer (NMSC) has a high and increasing incidence all over the world. Solar radiation is the main aetiology for humans. Although most research into photocarcinogenesis uses UVB as a source of radiation, UVA is also carcinogenic in long term. Pomegranate (PGE) and cocoa (CE) extracts have been used for medicinal purposes for time immemorial. Recently, it has been claimed that some of their properties may be an effective preventative measure against photocarcinogenesis and photoaging, but to date in vivo models have not been tested using RUVA, the objective of the present work. A lower incidence of lesions was observed in SKH-1 mice treated with PGE (p<0.001), and lower incidence of invasive squamous carcinoma in both treatment groups (p<0.001 for PGE and p<0.05 for CE); the PGE group also showed a lower level of cell proliferation than the control group (p<0.001). Significantly greater p53 alteration was observed in the control group than the treatment groups (p<0.001 for PGE and p = 0.05 for CE). No significant differences were found in relation to TIMP-1 and MMP-9. Taken together, the results suggest that oral feeding of PGE and CE to SKH-1 mice affords substantial protection against the adverse effects of RUVA, especially PGE.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chemopreventive effect of pomegranate and cocoa extracts on ultraviolet radiation-induced photocarcinogenesis in SKH-1 mice

Gómez-García¹,

López²,

Sánchez³

et al. 2020

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) belongs to NMSC and are predominant human malignancies worldwide (Zakharov et al, 2019). Mostly the non‐melanoma skin cancer (75–85%) are basal cell carcinomas, while SCC which are more likely to transmit to regional and local lymph nodes (LNs) are only 15–25% (Duarte et al, 2018). Skin cancer that evolved from basal cells containing pigments known as melanocytes at the bottom of epidermis are called basal‐cell carcinoma (BCC).…”

Section: Introductionmentioning

confidence: 99%

Multimodal imaging of skin lesions by using methylene blue as cancer biomarker

Malik

Andleeb

Ullah

2020

Microscopy Res & Technique

View full text Add to dashboard Cite

This study aimed the optical imaging of malignant and normal skin tissues with multimodal wide-field fluorescence polarization imaging (WF) technique, by using methylene blue as fluorescence dye. We present optical imaging of skin tissues by different techniques, including reflectance, fluorescence, and polarization imaging for early detection of skin cancer. We collected the reflectance confocal images at 390 and 500 nm. For wide-field fluorescence images, specimens were stimulated at 640 nm and images were collected between 670 and 710 nm. The correlation of the regarded optical modalities with histopathology (H&E), their potentials, capabilities, and limitations to detect skin lesions are discussed. The advantages of multimodal imaging of skin tissues are analyzed to divulge possibilities for precise tumor boundary detection and their classification for malignant and nonmalignant skin tissues. Prior to imaging, the cells were stained in aqueous MB (a dye approved by FDA).

show abstract

“…4 MDDK'lerde mortalite nadirdir, ancak gerek sık görülmeleri gerekse lokal yayılım ve destrüksiyon kabiliyetleri nedeni ile ülke ekonomilerinde önemli yer tutarlar. 5,6 MDDK tanımı genel olarak melanosit dışı bir hücreden köken alan deri kanserlerini yansıtırken, günlük pratikte bu terim genellikle keratinosit kaynaklı bazal hücreli karsinom (BHK) ve skuamöz hücreli karsinom (SHK) için kullanılmaktadır. BHK'ler MDDK'lerin yaklaşık %80'ini, SHK'ler ise %20'sini oluştururken, diğer karsinomlar MDDK'nin %1'den azını oluştururlar.…”

unclassified

Clinical, Histopathological and Laboratory Characteristics of Non-melanoma Skin Cancers: A Retrospective, Single-Center Study of 483 Patients

Hayran¹,

Uysal²,

Atilan³

et al. 2020

Turkiye Klinikleri J Med Sci

View full text Add to dashboard Cite

Skin cancer healthcare impact: A nation-wide assessment of an administrative database

Cited by 20 publications

References 43 publications

Chemopreventive effect of pomegranate and cocoa extracts on ultraviolet radiation-induced photocarcinogenesis in SKH-1 mice

Chemopreventive effect of pomegranate and cocoa extracts on ultraviolet radiation-induced photocarcinogenesis in SKH-1 mice

Multimodal imaging of skin lesions by using methylene blue as cancer biomarker

Clinical, Histopathological and Laboratory Characteristics of Non-melanoma Skin Cancers: A Retrospective, Single-Center Study of 483 Patients

Contact Info

Product

Resources

About