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Cited by 15 publications
(13 citation statements)
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“…Recently, a special issue of Journal of Biomedical Nanotechnology (www.aspbs.com/jbn) solely focused on nanotechnology as it pertains to skin care has been published. [91][92][93][94][95][96][97][98][99][100][101][102][103][104][105][106] Nohynek et al 107 111 reported zinc oxide nanoparticles induced genotoxicity in primary human epidermal keratinocytes. The biological interactions of ZnO nanoparticles in primary human epidermal keratinocytes (HEK) were investigated by scanning electron microscopy.…”
Section: Cosmetics and Toxicity Of Nanoparticlesmentioning
confidence: 99%
“…Recently, a special issue of Journal of Biomedical Nanotechnology (www.aspbs.com/jbn) solely focused on nanotechnology as it pertains to skin care has been published. [91][92][93][94][95][96][97][98][99][100][101][102][103][104][105][106] Nohynek et al 107 111 reported zinc oxide nanoparticles induced genotoxicity in primary human epidermal keratinocytes. The biological interactions of ZnO nanoparticles in primary human epidermal keratinocytes (HEK) were investigated by scanning electron microscopy.…”
Section: Cosmetics and Toxicity Of Nanoparticlesmentioning
confidence: 99%
“…Some eNMs including quantum dots (QDs) and ZnO nanoparticles do exhibit unique fluorescent and/or nonlinear optical signatures that can help distinguish penetration of intact particles from ions, but the detection sensitivity can be limited by tissue autofluorescence . Nonetheless, despite these complexities, progress is being made toward advancing our understanding of eNM skin interactions and our ability to draw conclusions about nanotechnology skin safety, as can be gleaned from many recent reviews …”
Section: Engineered Nanomaterials Skin Interactionsmentioning
confidence: 99%
“…107,[110][111][112][113][114] Nonetheless, despite these complexities, progress is being made toward advancing our understanding of eNM skin interactions and our ability to draw conclusions about nanotechnology skin safety, as can be gleaned from many recent reviews. 2,3,12,14,15,[115][116][117] In general, substances that contact skin have three basic mechanisms to penetrate the SC barrier-transcellular through corneocytes, intercellular between corneocytes, and penetration via skin appendages (e.g., sweat glands and the follicular infundibulum). 118 The transcellular route is considered to be of little importance because the corneocyte cell membrane (cornified envelop) is highly impermeable although this is somewhat still debated.…”
Section: Engineered Nanomaterials Skin Interactionsmentioning
confidence: 99%
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“…It is thought that in healthy skin, nanoparticles delivery pose minimal health risk because they mostly utilize biodegradable particles . Even as the stability and low toxicity of some nanoparticles have been exploited in several setting, the current knowledge of their toxicity effects is comparatively inadequately documented . However, available data suggest nanoparticles can bypass the protective barriers, being distributed and accumulate in several organs, with documented toxicity in several organ systems excluding the skin .…”
Section: Current Translational Therapeutic Approachesmentioning
confidence: 99%