Skeletal Morphogenesis and Anomalies in Gilthead Seabream: A Comprehensive Review

Abstract

The gilthead seabream, one of the most important species in Mediterranean aquaculture, with an increasing status of exploitation in terms of production volume and aquafarming technologies, has become an important research topic over the years. The accumulation of knowledge from several studies conducted during recent decades on their functional and biological characteristics has significantly improved their aquacultural aspects, namely their reproductive success, survival, and growth. Despite the remarkable progress in the aquaculture industry, hatchery conditions are still far from ideal, resulting in frequent abnormalities at the beginning of intensive culture, entailing significant economic losses. Those deformities are induced during the embryonic and post-embryonic periods of life, and their development is still poorly understood. In the present review, we created a comprehensive synthesis that covers the various aspects of skeletal morphogenesis and anomalies in the gilthead seabream, highlighting the genetic, environmental, and nutritional factors contributing to bone deformities and emphasized the potential of the gilthead seabream as a model organism for understanding bone morphogenesis in both aquaculture and translational biological research. This review article addresses the existing lack in the literature regarding gilthead seabream bone deformities, as there are currently no comprehensive reviews on this subject.

Urtica dioica Extract Abrogates Chlorpyrifos-Induced Toxicity in Zebrafish Larvae

“…During the past decade, teleost fish have been introduced as successful vertebrate models in scientific research [ 14 , 15 , 16 , 17 ], emphasizing zebrafish species ( Danio rerio ) [ 18 , 19 ]. Zebrafish offer multifaceted advantages in developmental neurotoxicity testing, as seen in the concordance between zebrafish and human neurodevelopmental pathways reported in many studies [ 5 , 20 , 21 ].…”