Six-Year Follow-up of an Idiopathic Retinal Vasoproliferative Tumor

Vasoproliferative tumours of the retina

“…8 9 12 13 Essentially, these benign lesions represent reactive gliovascular proliferations, with varying degrees of both gliosis and of vascular proliferation, as demonstrated in the histopathological specimens in our series (Fig1H–J, Fig 2E) and by others 18 14 Whether the gliosis or the vascular component is the initiating or driving element in this process remains a point of conjecture and requires further investigation.…”

Vasoproliferative tumours of the retina

“…8 9 12 13 Essentially, these benign lesions represent reactive gliovascular proliferations, with varying degrees of both gliosis and of vascular proliferation, as demonstrated in the histopathological specimens in our series (Fig1H–J, Fig 2E) and by others 18 14 Whether the gliosis or the vascular component is the initiating or driving element in this process remains a point of conjecture and requires further investigation.…”

Vasoproliferative retinal tumors: Clinical presentation and treatment outcome

“…The natural history of VPRTs is quite variable with slow progression seen in very few cases, while rapid progression associated with fibroglial proliferation and tractional retinal detachment has been described. 20,21 Despite the benign nature of the tumor and peripheral location, tumor-related complications such as intra/subretinal exudation, vitreous hemorrhage, CME and ERM have been reported to lead to visual impairment. [3][4][5]22 Due to relative rarity and variable natural course of the disease, the current literature lacks an evidence-based treatment protocol.…”

Trans‐vitreal endoresection for vasoproliferative retinal tumours

“…There is no consensus for the satisfactory management of vision‐threatening VPRTs. Observation is recommended if a small, peripheral lesion is not causing macula‐threatening exudation 7 . However, advanced cases may be associated with exudative maculopathy, sub‐retinal exudation, ERM formation and cystoid macular oedema, leading to irreversible visual function impairment.…”

Vasoproliferative tumours of the retina

“…8 9 12 13 Essentially, these benign lesions represent reactive gliovascular proliferations, with varying degrees of both gliosis and of vascular proliferation, as demonstrated in the histopathological specimens in our series (Fig1H–J, Fig 2E) and by others 18 14 Whether the gliosis or the vascular component is the initiating or driving element in this process remains a point of conjecture and requires further investigation.…”

Vasoproliferative retinal tumors: Clinical presentation and treatment outcome

“…The natural history of VPRTs is quite variable with slow progression seen in very few cases, while rapid progression associated with fibroglial proliferation and tractional retinal detachment has been described. 20,21 Despite the benign nature of the tumor and peripheral location, tumor-related complications such as intra/subretinal exudation, vitreous hemorrhage, CME and ERM have been reported to lead to visual impairment. [3][4][5]22 Due to relative rarity and variable natural course of the disease, the current literature lacks an evidence-based treatment protocol.…”

Trans‐vitreal endoresection for vasoproliferative retinal tumours

“…There is no consensus for the satisfactory management of vision‐threatening VPRTs. Observation is recommended if a small, peripheral lesion is not causing macula‐threatening exudation 7 . However, advanced cases may be associated with exudative maculopathy, sub‐retinal exudation, ERM formation and cystoid macular oedema, leading to irreversible visual function impairment.…”

Vasoproliferative tumours of the retina

“…8 9 12 13 Essentially, these benign lesions represent reactive gliovascular proliferations, with varying degrees of both gliosis and of vascular proliferation, as demonstrated in the histopathological specimens in our series (Fig1H–J, Fig 2E) and by others 18 14 Whether the gliosis or the vascular component is the initiating or driving element in this process remains a point of conjecture and requires further investigation.…”

Vasoproliferative retinal tumors: Clinical presentation and treatment outcome

“…The natural history of VPRTs is quite variable with slow progression seen in very few cases, while rapid progression associated with fibroglial proliferation and tractional retinal detachment has been described. 20,21 Despite the benign nature of the tumor and peripheral location, tumor-related complications such as intra/subretinal exudation, vitreous hemorrhage, CME and ERM have been reported to lead to visual impairment. [3][4][5]22 Due to relative rarity and variable natural course of the disease, the current literature lacks an evidence-based treatment protocol.…”

Trans‐vitreal endoresection for vasoproliferative retinal tumours

“…There is no consensus for the satisfactory management of vision‐threatening VPRTs. Observation is recommended if a small, peripheral lesion is not causing macula‐threatening exudation 7 . However, advanced cases may be associated with exudative maculopathy, sub‐retinal exudation, ERM formation and cystoid macular oedema, leading to irreversible visual function impairment.…”