Sister Elizabeth Kenny, an Australian Nurse, and Treatment of Poliomyelitis Victims

Oppewal, Sonda

doi:10.1111/j.1547-5069.1997.tb01145.x

Cited by 8 publications

(6 citation statements)

References 5 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reduced arthritic disease seen at 30°C was therefore due to effects mediated within the first 4 days post infection, the period of significant IFNα/β production and peak viral replication. These experiments (i) support the view that the ambient temperature mediates its effects during the time of IFNα/β production, and (ii) argue that any warming treatment attempting to reduce arthritic disease [ 1 , 2 ] likely needs to be initiated very early in infection.…”

Section: Resultssupporting

confidence: 63%

“…Studying the role of temperature in regulating viral infections and viral pathologies has an eclectic history. The Australian nurse, Elizabeth Kenny (1880–1952), pioneered the treatment of polio with application of heat packs to affected limbs [ 1 , 2 ], although the mechanistic basis for this treatment has not been identified [ 3 ]. A number of reasons for the increase in respiratory tract infections during the winter months have been proposed, with in vitro experiments in cell lines suggesting a role for improved type I interferon (IFN) responses at 37°C compared with lower temperatures [ 4 – 6 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis

et al. 2017

View full text Add to dashboard Cite

Chikungunya virus (CHIKV) belongs to a group of mosquito-borne alphaviruses associated with acute and chronic arthropathy, with peripheral and limb joints most commonly affected. Using a mouse model of CHIKV infection and arthritic disease, we show that CHIKV replication and the ensuing foot arthropathy were dramatically reduced when mice were housed at 30°C, rather than the conventional 22°C. The effect was not associated with a detectable fever, but was dependent on type I interferon responses. Bioinformatics analyses of RNA-Seq data after injection of poly(I:C)/jetPEI suggested the unfolded protein response and certain type I interferon responses are promoted when feet are slightly warmer. The ambient temperature thus appears able profoundly to effect anti-viral activity in the periphery, with clear consequences for alphaviral replication and the ensuing arthropathy. These observations may provide an explanation for why alphaviral arthropathies are largely restricted to joints of the limbs and the extremities.

show abstract

Section: Resultssupporting

confidence: 63%

Section: Introductionmentioning

confidence: 99%

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Kenny was an Australian “nurse” who had practiced independent of a physician in the bush (Paul, 1971). There is no formal record of Kenny completing a formal training course or applying for registration or certification as a nurse; however, she considered herself, and was considered by others to be a nurse (Oppewal, 1997). Her independent spirit enabled her to challenge the traditional methods of treating polio and develop new methods.…”

Section: The Nfip and Nursingmentioning

confidence: 99%

Trumpets of Attack: Collaborative Efforts Between Nursing and Philanthropies to Care for the Child Crippled with Polio 1930 to 1959

Carter

2001

Public Health Nursing

View full text Add to dashboard Cite

The purpose of this historical inquiry research was to explore (a) the relationship of nursing and foundations focusing on polio from 1930 to 1959; (b) the employment and educational opportunities arising from the polio epidemics for white and black nurses, as well as the obstacles encountered; (c) the role of nursing leaders in the care of the crippled child; and (d) the effects of the resolution of the polio epidemics resulting from the polio vaccine on public attitude and on the philanthropic organizations. Relevant journals, primary and secondary sources, and personal interviews were the methods used for data collection. Because of the extraordinary community support for work related to polio, nurses were able to obtain support from foundations. This support resulted in employment and educational opportunities for bedside nursing, primarily for white nurses. Middle and upper class fear of polio enabled the development of powerful and successful private organizations to supplement the available governmental services. This research illustrates the advances that nursing has made and reminds nurses to develop and maintain strong praxis relationships, alliances with philanthropies, referrals for clients with local organizations, and a strong voice in the planning arena.

show abstract

“…One of the earliest descriptions regarding management strategies of polio is the heroic work of Sister Elizabeth Kenny (an Australian nurse). She used hot packs to relieve muscle spasms in early stages of the disease 13 and discouraged the practice of prolonged immobilization of affected limbs. A large number of patients were benefited.…”

Section: Managementmentioning

confidence: 99%

Poliomyelitis

Mehndiratta

Pande

2014

The Neurohospitalist

101

View full text Add to dashboard Cite

Poliomyelitis is a highly infectious disease caused by a virus belonging to the Picornaviridae family. It finds a mention even in ancient Egyptian paintings and carvings. The clinical features are varied ranging from mild cases of respiratory illness, gastroenteritis, and malaise to severe forms of paralysis. These have been categorized into inapparent infection without symptoms, mild illness (abortive poliomyelitis), aseptic meningitis (nonparalytic poliomyelitis), and paralytic poliomyelitis. This disease has been associated with crippling deformities affecting thousands of lives throughout the world. Only due to the perseverance and determination of great scientists in 1900s, the genomic structure of the virus and its pathogenesis could be elucidated. Contribution of Salk and Sabin in the form of vaccines-oral polio vaccine (OPV) and the inactivated polio vaccine-heralded a scientific revolution. In 1994, the World Health Organization (WHO) Region of The Americas was certified polio free followed by the WHO Western Pacific Region in 2000 and the WHO European Region in June 2002 of the 3 types of wild poliovirus (types 1, 2, and 3). In 2013, only 3 countries remained polio endemic-Nigeria, Pakistan, and Afghanistan. Global eradication of polio is imperative else the threat of an outbreak will hover forever. Today, all the governments of the world in collaboration with WHO stand unified in their fight against poliomyelitis and the task when achieved will pave the way for eliminating other infections in future.

show abstract

Sister Elizabeth Kenny, an Australian Nurse, and Treatment of Poliomyelitis Victims

Cited by 8 publications

References 5 publications

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis

Trumpets of Attack: Collaborative Efforts Between Nursing and Philanthropies to Care for the Child Crippled with Polio 1930 to 1959

Poliomyelitis

Contact Info

Product

Resources

About