ÖzAmaç: Bu çalışmanın amacı nazal septum deviasyonu, konka bulloza, osteomeatal kompleks tıkanıklığı ve odontojenik lezyon varlığının, maksiller sinüs mukozal kalınlaşmasıyla olan potansiyel ilişkisinin ortaya konmasıdır. Gereç ve Yöntemler: İki yüz hastaya (101 erkek, 99 kadın) ait 396 maksiller sinüsün konik ışınlı bilgisayarlı tomografi görüntülerinde; maksiller sinüs mukozal kalınlaşmasıyla ilişkili nazal septum deviasyonu, konka bulloza, osteomeatal kompleks tıkanıklığı ve odontojenik lezyon varlığına bakılmıştır. Bulgular: Yüz on dokuz hastada (%59) nazal septal deviasyon, 100 hastada (%50) en az bir konka bulloza, 26 hastada (%13) en az bir tarafta osteomeatal kompleks Objective: The objective of this study was to establish the prevalence of nasal septal deviation, concha bullosa, and osteomeatal complex disease (obstruction), and odontogenic lesions, along with their potential relationships with maxillary sinus mucosal thickening. Materials and Methods: (CBCT) images of 200 patients (101 males, 99 females) with 396 exposed maxillary sinuses, were inspected for presence of nasal septal deviation, concha bullosa, osteomeatal complex disease (obstruction), and odontogenic lesions related to maxillary sinus and maxillary sinus mucosal thickening. Result: One hundred nineteen patients (59%) had nasal septal deviation, 100 (50%) had at least one concha bullosa, 26 (13%) had osteomeatal complex disease on at least one side, 39 (19.5%) had odontogenic lesions related to maxillary sinuses, and 112 (56%) had evidence of mucosal thickening. There was a statistically significant relationship among osteomeatal complex disease, odontogenic lesion and maxillary sinus mucosal thickening (p=0.00). No statistically significant relationship could be established among the presence of concha bullosa, nasal septal deviation and maxillary sinus mucosal thickening (p>0.05). Conclusion: Odontogenic lesions and osteomeatal complex diseases have association with maxillary sinus mucosal thickening. CBCT imaging could be a diagnostic tool for assessment potential reasons of maxillary sinus mucosal thickening.