Sinonasal Neoplasia – Clinicopathological Profile And Importance of Computed Tomography

Clinicopathologic profile of sinonasal neoplasia in Kano, Northwestern Nigeria: A 10-year single-institution experience

“…[ 15 ] Reports from similar studies in Asia and Nigeria showed a preponderance of male patients with sinonasal neoplasm in alignment with our finding. [ 15 22 23 24 ] The youngest patient in our series was 1 year 6 months having embryonal rhabdomyosarcoma, similar to what Wang et al . reported in their series from China.…”

Paranasal sinus lymphoma: Retrospective review with focus on clinical features, histopathology, prognosis, and relationship to systemic lymphoma

“…Sinonasal malignancies represent approximately 3% of head and neck cancers and <1% of all systemic malignancies . The majority of sinonasal malignancies are epithelial in nature, the most common of which is squamous cell carcinoma (globally accounting for approximately 50% of the cases) . Sinonasal lymphoid neoplasms occur much less frequently, constituting <1% of all head and neck cancers .…”

Imaging Appearance ofSMARCB1(INI1)-Deficient Sinonasal Carcinoma: A Newly Described Sinonasal Malignancy

“…However, this is the case in most aggressive sinonasal malignancies. 6,8,12,13 We found a predilection for central structures, with 13 of 17 tumors described as nasal or nasoethmoidal in origin, with frequent invasion into the adjacent orbital and intracranial compartments. Other sinonasal malignancies such as sinonasal undifferentiated carcinoma, esthesioneuroblastoma, lymphoma, and melanoma arise most frequently in the superior nasal cavity with similar patterns of invasion.…”

“…The tendency toward avid enhancement, intermediate T2 signal intensity, moderate diffusion restriction, and FDG avidity demonstrated in our series is characteristic for sinonasal undifferentiated carcinoma and squamous cell carcinoma, which, though occurring most commonly in the paranasal sinuses (75%), must still be considered when nasal cavity masses are identified because of the high relative prevalence of this diagnosis. [1][2][3][4]7,12 CT imaging demonstrated associated calcification in close to half of the tumors (6 of 13), though no tumor calcification was reported on histopathologic analysis. In considering this discrepancy, we felt that calcification might reflect retained bone fragments in 2 patients and an aggressive periosteal reaction in 4.…”

“…Nevertheless, our observed frequency of calcification on CT exceeds that reported in the literature, and the perpendicular "hair on end" appearance suggesting aggressive periosteal reaction is a particularly unusual feature. 5,7,12,14 A more accurate estimation of the incidence of this and other imaging features, and of their potential utility as indicators of this disease, will require a larger sample size.…”