Single-Photon Tomographic Study of Regional Cerebral Blood Flow in Epilepsy

Regional Cerebral Blood Flow during Interictal State: Differences between Temporal Lobe Epilepsy and Primary Generalized Epilepsy

“…The hypoperfusion in distant brain areas was always less marked than in the temporal epileptic focus. Similar results showing interictal decrease in rCBF in partial epilepsy has been reported by others using various techniques including two-dimen sional method [15,24], single photon emis sion tomography [2] and PET [9], Likewise an interictal reduced glucose metabolism has been found in temporal lobe and in distant areas of epileptic patients studied by PET with 18-Fluoro-dcoxy-glucose [6]. The hy perperfusion of epileptic focus reported in prior interictal studies performed by the in traarterial Xenon method can be explained either by the cortical localization of the lesion and its tumoral nature [ 13] or by the suberitical activation induced by photic stimulation used during the CBF measurement [25].…”

Regional Cerebral Blood Flow during Interictal State: Differences between Temporal Lobe Epilepsy and Primary Generalized Epilepsy

“…The hypoperfusion in distant brain areas was always less marked than in the temporal epileptic focus. Similar results showing interictal decrease in rCBF in partial epilepsy has been reported by others using various techniques including two-dimen sional method [15,24], single photon emis sion tomography [2] and PET [9], Likewise an interictal reduced glucose metabolism has been found in temporal lobe and in distant areas of epileptic patients studied by PET with 18-Fluoro-dcoxy-glucose [6]. The hy perperfusion of epileptic focus reported in prior interictal studies performed by the in traarterial Xenon method can be explained either by the cortical localization of the lesion and its tumoral nature [ 13] or by the suberitical activation induced by photic stimulation used during the CBF measurement [25].…”

Interictal regional cerebral blood flow during non specific activation test in partial epilepsy.

“…Twenty one of 25 epileptic patients showed an abnormal rCBF pattern during photic stimulation (table 1). For 16 (cases 1-16) of 19 epileptic patients with stable EEG epileptic focus (cases [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19], an activation index increase and/or a greater asymmetries was observed in the suspected epileptic focus: one subject (case 13) showed only a rCBF activation in the region corresponding to resting hypoperfusion and epileptic EEG abnormalities, three patients (cases 14,15,16) demonstrated only an asymmetry greater for the epileptic region than the homologous contralateral one and the 12 others showed both an activation and a greater asymmetry in the region of the stable epileptic focus. Moreover eight Table 3 index in the region corresponding to the site of the greater asymmetry.…”

Normal Distribution of Regional Cerebral Blood Flow Measured by Dynamic Single-Photon Emission Tomography

“…Previously published results from our laboratory in patients suffering from stroke (Bonte and Stokely, 1981), epilepsy (Bonte et aI. , 1983a), and arteriovenous malformations (Bonte et aI.…”

Regional Cerebral Blood Flow during Interictal State: Differences between Temporal Lobe Epilepsy and Primary Generalized Epilepsy

“…The hypoperfusion in distant brain areas was always less marked than in the temporal epileptic focus. Similar results showing interictal decrease in rCBF in partial epilepsy has been reported by others using various techniques including two-dimen sional method [15,24], single photon emis sion tomography [2] and PET [9], Likewise an interictal reduced glucose metabolism has been found in temporal lobe and in distant areas of epileptic patients studied by PET with 18-Fluoro-dcoxy-glucose [6]. The hy perperfusion of epileptic focus reported in prior interictal studies performed by the in traarterial Xenon method can be explained either by the cortical localization of the lesion and its tumoral nature [ 13] or by the suberitical activation induced by photic stimulation used during the CBF measurement [25].…”

Interictal regional cerebral blood flow during non specific activation test in partial epilepsy.

“…Twenty one of 25 epileptic patients showed an abnormal rCBF pattern during photic stimulation (table 1). For 16 (cases 1-16) of 19 epileptic patients with stable EEG epileptic focus (cases [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19], an activation index increase and/or a greater asymmetries was observed in the suspected epileptic focus: one subject (case 13) showed only a rCBF activation in the region corresponding to resting hypoperfusion and epileptic EEG abnormalities, three patients (cases 14,15,16) demonstrated only an asymmetry greater for the epileptic region than the homologous contralateral one and the 12 others showed both an activation and a greater asymmetry in the region of the stable epileptic focus. Moreover eight Table 3 index in the region corresponding to the site of the greater asymmetry.…”

Normal Distribution of Regional Cerebral Blood Flow Measured by Dynamic Single-Photon Emission Tomography

“…Previously published results from our laboratory in patients suffering from stroke (Bonte and Stokely, 1981), epilepsy (Bonte et aI. , 1983a), and arteriovenous malformations (Bonte et aI.…”

Regional Cerebral Blood Flow during Interictal State: Differences between Temporal Lobe Epilepsy and Primary Generalized Epilepsy

“…The hypoperfusion in distant brain areas was always less marked than in the temporal epileptic focus. Similar results showing interictal decrease in rCBF in partial epilepsy has been reported by others using various techniques including two-dimen sional method [15,24], single photon emis sion tomography [2] and PET [9], Likewise an interictal reduced glucose metabolism has been found in temporal lobe and in distant areas of epileptic patients studied by PET with 18-Fluoro-dcoxy-glucose [6]. The hy perperfusion of epileptic focus reported in prior interictal studies performed by the in traarterial Xenon method can be explained either by the cortical localization of the lesion and its tumoral nature [ 13] or by the suberitical activation induced by photic stimulation used during the CBF measurement [25].…”

Interictal regional cerebral blood flow during non specific activation test in partial epilepsy.

“…Twenty one of 25 epileptic patients showed an abnormal rCBF pattern during photic stimulation (table 1). For 16 (cases 1-16) of 19 epileptic patients with stable EEG epileptic focus (cases [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19], an activation index increase and/or a greater asymmetries was observed in the suspected epileptic focus: one subject (case 13) showed only a rCBF activation in the region corresponding to resting hypoperfusion and epileptic EEG abnormalities, three patients (cases 14,15,16) demonstrated only an asymmetry greater for the epileptic region than the homologous contralateral one and the 12 others showed both an activation and a greater asymmetry in the region of the stable epileptic focus. Moreover eight Table 3 index in the region corresponding to the site of the greater asymmetry.…”

Normal Distribution of Regional Cerebral Blood Flow Measured by Dynamic Single-Photon Emission Tomography

“…Previously published results from our laboratory in patients suffering from stroke (Bonte and Stokely, 1981), epilepsy (Bonte et aI. , 1983a), and arteriovenous malformations (Bonte et aI.…”