1990
DOI: 10.1001/archderm.126.3.398
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Single dose of albendazole in the treatment of cutaneous larva migrans

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Cited by 8 publications
(8 citation statements)
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“…For 98% of the investigated patients, cure was achieved within 10 days by the topical application of thiabendazole ointment only. For two patients with extensive, disseminated infections, treatment with single oral doses ofthiabendazole and albendazole was preferred [13][14][15][16][17]. The frequently severe itching ceased rapidly for all patients following the application of antihelmintic agents.…”
Section: Discussionmentioning
confidence: 99%
“…For 98% of the investigated patients, cure was achieved within 10 days by the topical application of thiabendazole ointment only. For two patients with extensive, disseminated infections, treatment with single oral doses ofthiabendazole and albendazole was preferred [13][14][15][16][17]. The frequently severe itching ceased rapidly for all patients following the application of antihelmintic agents.…”
Section: Discussionmentioning
confidence: 99%
“…Clinical trials of albendazole therapy for CLMs have failed to establish the optimal dosage regimen. Cure rates of 100% have been reported with a single dose of 400 mg [10], 400 mg/day for three [11] and five [12] consecutive days, and 800 mg/day for three consecutive days [11,13]. However, in the largest study, 400 mg/day albendazole for five consecutive days failed in two of 26 Italian tourists [14].…”
Section: Albendazolementioning
confidence: 99%
“…Our cases confirm the efficacy and safety of albendazole in the treatment CLM. The patient relapsing suggests once more [4,5] that the recommended dose would be 400 mg daily for 5 days, and it should not be reduced to a single 400 mg/day dose [6] or 400 mg/day dose for only three days as previously reported [1,2,3].…”
Section: Larva Migrans: Report Of Three Cases Therapeutic Advicementioning
confidence: 98%
“…Other treatments include thiabendazole administered systematically, but this is associated with possibly severe side-effects, or topically with or without occlusions, however this may be difficuh depending on the site. Furthermore thiabendazole is unavailable in many countries [6].…”
Section: Larva Migrans: Report Of Three Cases Therapeutic Advicementioning
confidence: 99%
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