Simultaneous visualization of spatial and chromatic aberrations by two-dimensional Fourier transform spectral interferometry

Amir, Wafa; Planchon, Thomas A.; Durfee, Charles G.; Squier, Jeffrey A.; Gabolde, Pablo; Trebino, Rick; Müller, Markus

doi:10.1364/ol.31.002927

Cited by 47 publications

(33 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In multiphoton microscopy, spatial aberrations are ultimately coupled to temporal distortions. The extent of this coupling can be precisely determined by using two-dimensional spectral interferometry (2DSI) [13]. Specifically, one can extract the impact of the spatial distortions on pulse duration.…”

Section: Experimental Methodsmentioning

confidence: 99%

“…For example, 2DSI measurements on a 1.25 NA Zeiss objective indicated that for pulse durations greater than 50 fs, spherical aberration is dominant, and while the focus broadens spatially as a result of this distortion, the impact on pulse duration is negligible. Conversely, for pulse durations on the order of 15 fs, the chromatic aberration is dominant, and will result in broadening the pulse duration to approximately 25 fs [13]. In the case of these very short pulses, distortions are a complex mix of radially varying aberrations.…”

Section: Experimental Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Optimizing the fluorescent yield in two-photon laser scanning microscopy with dispersion compensation

Field¹,

Carriles²,

Sheetz³

et al. 2010

Opt. Express

View full text Add to dashboard Cite

A challenge for nonlinear imaging in living tissue is to maximize the total fluorescent yield from each fluorophore. We investigated the emission rates of three fluorophores – rhodamine B, a red fluorescent protein, and CdSe quantum dots – while manipulating the phase of the laser excitation pulse at the focus. In all cases a transform-limited pulse maximized the total yield to insure the highest signal-to-noise ratio. Further, we find evidence of fluorescence anti-bleaching in quantum dot samples.

show abstract

Section: Experimental Methodsmentioning

confidence: 99%

Section: Experimental Methodsmentioning

confidence: 99%

Optimizing the fluorescent yield in two-photon laser scanning microscopy with dispersion compensation

Field¹,

Carriles²,

Sheetz³

et al. 2010

Opt. Express

View full text Add to dashboard Cite

show abstract

“…One of the most common methods used for the measurement of spectral phase shift is the so-called spectrally resolved interferometry, SRI [63][64][65][66][67][68][69][70][71][72], which can be interpreted as a special case of SSRI when α = 0. The beams here leave the Michelson or Mach-Zehnder interferometer in a collinear manner, and an interference is established due to the temporal delay t* within the time scale of the coherence time, kept to be constant between the beams.…”

Section: Spectrally Resolved Interferometrymentioning

confidence: 99%

What We Can Learn about Ultrashort Pulses by Linear Optical Methods

2013

View full text Add to dashboard Cite

Spatiotemporal compression of ultrashort pulses is one of the key issues of chirped pulse amplification (CPA), the most common method to achieve high intensity laser beams. Successful shaping of the temporal envelope and recombination of the spectral components of the broadband pulses need careful alignment of the stretcher-compressor stages. Pulse parameters are required to be measured at the target as well. Several diagnostic techniques have been developed so far for the characterization of ultrashort pulses. Some of these methods utilize nonlinear optical processes, while others based on purely linear optics, in most cases, combined with spectrally resolving device. The goal of this work is to provide a review on the capabilities and limitations of the latter category of the ultrafast diagnostical methods. We feel that the importance of these powerful, easy-to-align, high-precision techniques needs to be emphasized, since their use could gradually improve the efficiency of different CPA systems. We give a general description on the background of spectrally resolved linear interferometry and demonstrate various schematic experimental layouts for the detection of material dispersion, angular dispersion and carrier-envelope phase drift. Precision estimations and discussion of potential applications are also provided.

show abstract

“…44 Finally, it should be noted that entirely linear, interferometric methods can be used to characterize the focus. 40,45,46 Jasapara et al used spectrally resolved interferometry to characterize how 10 fs pulses were distorted when focused by a 205 and a 1005 0.85 NA. objectives.…”

Section: B Characterization Of Pulses At the Focus Of A High Na Opticmentioning

confidence: 99%

Invited Review Article: Imaging techniques for harmonic and multiphoton absorption fluorescence microscopy

Carriles

Schafer²,

Sheetz³

et al. 2009

Review of Scientific Instruments

152

125

View full text Add to dashboard Cite

We review the current state of multiphoton microscopy. In particular, the requirements and limitations associated with high-speed multiphoton imaging are considered. A description of the different scanning technologies such as line scan, multifoci approaches, multidepth microscopy, and novel detection techniques is given. The main nonlinear optical contrast mechanisms employed in microscopy are reviewed, namely, multiphoton excitation fluorescence, second harmonic generation, and third harmonic generation. Techniques for optimizing these nonlinear mechanisms through a careful measurement of the spatial and temporal characteristics of the focal volume are discussed, and a brief summary of photobleaching effects is provided. Finally, we consider three new applications of multiphoton microscopy: nonlinear imaging in microfluidics as applied to chemical analysis and the use of two-photon absorption and self-phase modulation as contrast mechanisms applied to imaging problems in the medical sciences.

show abstract

Simultaneous visualization of spatial and chromatic aberrations by two-dimensional Fourier transform spectral interferometry

Cited by 47 publications

References 14 publications

Optimizing the fluorescent yield in two-photon laser scanning microscopy with dispersion compensation

Optimizing the fluorescent yield in two-photon laser scanning microscopy with dispersion compensation

What We Can Learn about Ultrashort Pulses by Linear Optical Methods

Invited Review Article: Imaging techniques for harmonic and multiphoton absorption fluorescence microscopy

Contact Info

Product

Resources

About