Simultaneous Bilateral Parotid and Submandibular Gland Calculi

Systemic diseases and the risk of developing salivary stones: a case control study

“…5,6,10,16 The distribution of salivary stones over the different salivary glands is also in accordance with previous reports. 5,9,18,20,21 In the present study, a small male preponderance was observed, which is in agreement with the study of Zenk et al 10 Older studies found a more extensive male preponderance. 4,5 A potential limitation of the present case control study is the use of data from medical records, which had not specifically been recorded for scientific purposes.…”

“…Two case reports suggested a possible relation between salivary stone formation and medication. Perrotta et al 18 described a 57-year-old woman with Parkinson disease and salivary stones in both the submandibular gland and the parotid gland and was treated with levodopa and amantadine. The authors suggested that the medication may have contributed to sialolith formation in this patient.…”

Lack of evidence that nephrolithiasis increases the risk of sialolithiasis: A longitudinal follow-up study using a national sample cohort

“…Unlike in nephrolithiasis, the literature points to no direct correlation between systemic factors such as calcium metabolism and sialolithiasis [ 1 , 36 ]. This finding is supported by the fact that the majority of salivary stones involve one salivary gland, and simultaneous sialolithiasis in multiple salivary glands is very rare [ 37 , 38 ]. Paterson et al have pointed out that although patients with hyperparathyroidism have high concentrations of calcium and phosphate in both urine and saliva, nephrolithiasis is common in that condition but sialolithiasis is relatively rare [ 39 ].…”

New modalities in the management of human sialolithiasis

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