Simplified technique for auxiliary orthotopic liver transplantation using a whole graft

Abstract

BackgroundAcute liver failure is associated with a high mortality rate and the main purposes of treatment are to prevent cerebral edema and infections, which often are responsible for patient death. The orthotopic liver transplantation is the gold standard treatment and improves the 1-year survival.AimTo describe an alternative technique to auxiliary liver transplant on acute liver failure.MethodWas performed whole auxiliary liver transplantation as an alternative technique for a partial auxiliary liver transplantation using a whole liver graft from a child removing the native right liver performed a right hepatectomy. The patient met the O´Grady´s criteria and the rational to indicate an auxiliary orthotopic liver transplantation was the acute classification without hemodynamic instability or renal failure in a patient with deterioration in consciousness.ResultsThe procedure improved liver function and decreased intracranial hypertension in the postoperative period.ConclusionThis technique can overcome some postoperative complications that are associated with partial grafts. As far as is known, this is the first case of auxiliary orthotopic liver transplantation in Brazil.

Dynamic Data-Driven Modeling for Ex Vivo Data Analysis: Insights into Liver Transplantation and Pathobiology

“…To fully harness the power of this technique, however, a proper understanding of the interplay among variable types is imperative, and computational modeling is the primary means of integrating such multivariate data. In this review, we focus on the application of dynamic data-driven a technique which uses a partial donor lobe to support the recipient organ [10,11], can be subdivided into three separate surgical techniques: heterotopic ALT, auxiliary partial orthotopic liver transplantation, and whole graft ALT [12,13].…”