Simple telephone call a feasible, useful and acceptable method of following up patients with cerebrovascular accidents: Prospective Cohort study in South India

Mishra, Ajay Kumar; Aaron, Sanjith; Abhilash, KundavaramPaul Prabhakar; Iyadurai, Ramya; Shaikh, Atif; Lazarus, Elizabeth; Alexander, Vijay; George, Anu Anna; Vishali, P; Sudarsanam, Thambu David

doi:10.1177/1747493016654486

Cited by 10 publications

(4 citation statements)

References 5 publications

(5 reference statements)

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“…Our study had several limitations; we did not have details of cardiac imaging, transesophageal echocardiogram, details of surgical management, details of recurrence, and long term outcomes on these patients [28][29][30]. The strength of our study was the sample size, longer duration of the study, availability of microbiological diagnosis, and antibiotics susceptibility pattern for all patients [31][32][33].…”

Section: Articlementioning

confidence: 99%

Gram-negative infective endocarditis: a retrospective analysis of 10 years data on clinical spectrum, risk factor and outcome

Thomas

Mishra

Jasmine

et al. 2020

Monaldi Arch Chest Dis

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Infective endocarditis (IE) is a significant cause of morbidity and mortality. Underlying congenital heart disease and acquired valvular disease significantly increases the IE risk, which is still prevalent in developing countries. Gram-negative organism related IE prevalence appears to be rising with limited data on their presentation and outcomes. This study hopes to shed further light on this subject. This retrospective cross-sectional study occurred in a tertiary care center in South India. A retrospective cross-sectional study performed in a single tertiary care center in South India. All patients with IE from 2006 to 2016 were included in this study. The details of clinical presentation, laboratory investigations, clinical course, microbiology, and outcomes were obtained. Patients fulfilling the modified Duke's criteria and a culture-proven diagnosis of gram-negative IE were eligible for inclusion. A total of 27 patients were enrolled from Jan 2006 to Dec 2016, among whom 78% were male. Prior structural heart disease was common in our cohort (41%) with renal (55%) and embolic (51%) complications being the most common systemic complications. A comparison of mortality with survivors found that congenital and acquired structural heart disease had a higher risk of mortality. Non-fermenting GNB accounted for 52% of the cohort, with Pseudomonas accounting for 19%. E. coli was the most common bacilli isolated, constituting 37% of the cohort. Assessment of risk factors for adverse outcomes found that renal dysfunction and intravascular device were significant with multivariate-logarithmic analysis showing renal dysfunction as an independent risk factor. In-hospital mortality in this series was 30%. In conclusion, gram-negative IE was more prevalent among males. Underlying structural heart disease was the most common risk factor associated with the disease. Renal dysfunction and embolic complications were the most common complications in this cohort. E. coli and NFGNB accounted for 70% of the offending organisms. In-hospital mortality was similar to patients with IE secondary to common organisms. The presence of renal dysfunction was an independent risk factor for an adverse outcome.

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Section: Articlementioning

confidence: 99%

Gram-negative infective endocarditis: a retrospective analysis of 10 years data on clinical spectrum, risk factor and outcome

Thomas

Mishra

Jasmine

et al. 2020

Monaldi Arch Chest Dis

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“…6 Table 1 shows the multiple stroke mimics that have been reported in the literature. [12][13][14]15,16 Future studies should incorporate broader differential and detailed workup.…”

Section: Identifying the Stroke Mimics And The Uncommon Causes Of Strokementioning

confidence: 99%

Identifying the Stroke Mimics

Mishra¹,

Vanjare²,

George³

et al. 2021

IJGM

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Individuals presenting with sudden and focal neurological findings are usually suspected to have stroke. However, there are other conditions that can simulate stroke, which are often referred to as stroke mimics. Awareness and understanding these stroke-like disorders are of extreme importance as the treatment of each of them might be variable. We hereby briefly discuss these stroke mimics, common differentials, and key features to differentiate amongst the various causes of acute neurological event. Stroke is one of the neurological emergencies that needs urgent intervention to prevent significant mortality and morbidity. At the same time, it is important to realize the importance of other conditions which may mimic to stroke. In this letter, we aim to discuss a few key features that could probably help to distinguish stroke from mimickers thereby helping emergency doctors, neurologists, and hospitalists in streamlining the correct treatment at the earliest.

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“…The roles of CNS depressants including opioids, benzodiazepines, neuromuscular blocking agents on case identification and screening for neurological deficits among critically ill patients still needs consideration [12,13,19]. Multiple medications that are used for treatment, their role in cerebrovascular events and long term outcome still require clarification [12,14,27]. The exact mechanisms with which patients suffer cerebrovascular events and how these events attribute to poor outcome require further understanding [28].…”

Section: Future Directionmentioning

confidence: 99%

Cerebrovascular events in COVID-19 patients

Mishra

Sahu

George

et al. 2020

Monaldi Arch Chest Dis

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Neurological manifestations in patients with COVID–19 are more frequently being reported. Cerebrovascular events have been reported in around 3% of patients. In this review we summarize the published literature on cerebrovascular events in patients with COVID-19 as available on the PubMed database. So far, 3 studies have reported cerebrovascular events. Cerebrovascular events were identified on screening patients with decreased consciousness or in the presence of focal neurological deficits. These events were common in elderly, critically ill patients and in patients with prior cardio-cerebrovascular comorbidities. The diagnosis of cerebrovascular events was confirmed with computed tomography of the brain in most studies reporting neurological events. Multiple pathological mechanisms have been postulated regarding the process of neurological and vascular injury among which cytokine storm is shown to correlate with mortality. Patients with severe illness are found to have a higher cardio- cerebrovascular comorbidity. With an increasing number of cases and future prospective studies, the exact mechanism by which these cerebrovascular events occur and attribute to the poor outcome will be better understood.

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Simple telephone call a feasible, useful and acceptable method of following up patients with cerebrovascular accidents: Prospective Cohort study in South India

Cited by 10 publications

References 5 publications

Gram-negative infective endocarditis: a retrospective analysis of 10 years data on clinical spectrum, risk factor and outcome

Gram-negative infective endocarditis: a retrospective analysis of 10 years data on clinical spectrum, risk factor and outcome

Identifying the Stroke Mimics

Cerebrovascular events in COVID-19 patients

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