2014
DOI: 10.1016/j.chroma.2014.07.074
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Simple semi-automated portable capillary electrophoresis instrument with contactless conductivity detection for the determination of β-agonists in pharmaceutical and pig-feed samples

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Cited by 64 publications
(42 citation statements)
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“…As for CE-C 4 D both the separation and detection of ions are based on electronic principles and the method only requires low-pressure uidic components; CE-C 4 D offers many advantageous features, including the possible translation into portable instrumentation, high conguration exibility and ease of construction and operation. Since the launch of the rst in-house-made (portable) CE instrument in 1998, 19 different prototypes have been developed and introduced by Hauser and co-workers, ranging from instruments with manual injection and ushing, [20][21][22] systems where this has been semi-automated 23 to fully automated single-channel versions [24][25][26][27] and dual-channel congurations using one common buffer. 28,29 In parallel, signicant contributions have been made by other groups to inhouse-built (portable) CE instrumentation.…”
Section: Introductionmentioning
confidence: 99%
“…As for CE-C 4 D both the separation and detection of ions are based on electronic principles and the method only requires low-pressure uidic components; CE-C 4 D offers many advantageous features, including the possible translation into portable instrumentation, high conguration exibility and ease of construction and operation. Since the launch of the rst in-house-made (portable) CE instrument in 1998, 19 different prototypes have been developed and introduced by Hauser and co-workers, ranging from instruments with manual injection and ushing, [20][21][22] systems where this has been semi-automated 23 to fully automated single-channel versions [24][25][26][27] and dual-channel congurations using one common buffer. 28,29 In parallel, signicant contributions have been made by other groups to inhouse-built (portable) CE instrumentation.…”
Section: Introductionmentioning
confidence: 99%
“…The obtained solution was subsequently evaporated and filled up to 25 mL with deionized water prior to CE-C 4 D analyses. For the determination of the REEs with CE-C 4 D, the capillary was flushed with the buffer before each separation (see more details on the manual mode in [39] and the semi-automated mode in [42]). Hydrodynamic sample injection was carried out by siphoning at 10 cm height for 10 s. Electrophoretic separations were implemented at a voltage of 15 kV.…”
Section: Methodsmentioning
confidence: 99%
“…These features also allow its use in compact portable CE instruments [35,36] for flexible mobile deployment, which can also be built in low cost versions [37,38]. Different portable and purpose-made CE-C 4 D configurations have been developed, ranging from instruments with manual operations (see [39][40][41] for example), semi-automated systems [42] to fully automated single-channel versions (refer to references [43][44][45][46] for more details) and multi-channel configurations [47][48][49][50]. Although REEs in the native form of inorganic ions can be seen as suitable candidates for CE-C 4 D, so far this methodology has to the best of our knowledge not been developed for this application.…”
Section: Introductionmentioning
confidence: 99%
“…Nguyen et al () reported a portable CE method with CE‐ 4 CD for the determination of some β ‐agonists, namely salbutamol, metoprolol and ractopamine, in pharmaceutical formulations. A buffer solution containing 10 m m arginine adjusted to pH 4.9 with acetic acid was employed as a BGE for separation of salbutamol, metoprolol and ractopamine.…”
Section: Pharmaceutical Analysismentioning
confidence: 99%