Simple and rapid method for 336 multiresidual pesticide analysis in saliva, determination of their chemical stabilities, and biomonitoring of farmers

Park, Eun‐Young; Lee, Jiho; Lee, Hye Suk; Kim, Jeong‐Han; Shin, Yongho

doi:10.1016/j.chemosphere.2022.136725

Cited by 8 publications

(5 citation statements)

References 44 publications

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“…Conventional QuEChERS methods showed a matrix effect of 70% in butachlor, which shows a stronger matrix effect than those of our study [ 47 ]. Therefore, the established method can be applicable for green vegetables, and it is possible to use the pure standard solutions for quantitation instead of the matrix-matched standard solutions [ 7 , 9 ].…”

Section: Resultsmentioning

confidence: 99%

“…Samples that have a higher dry matter content to total mass ratio usually produce a severe matrix effect. Samples with high water content, such as urine or saliva, tend to have a mild or negligible matrix effect, while samples with high levels of protein or fat, such as hair or livestock products, usually exhibit a strong matrix effect [ 5 , 6 , 7 , 8 , 9 ]. The matrix effect for crops can vary depending on their endogenous composition and biochemical characteristics.…”

Section: Introductionmentioning

confidence: 99%

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LC-MS/MS Method Minimizing Matrix Effect for the Analysis of Bifenthrin and Butachlor in Chinese Chives and Its Application for Residual Study

Kim

Lee

Jeong

et al. 2023

Foods

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The matrix effect refers to the change in the analytical signal caused by the matrix in which the sample is contained, as well as the impurities that are co-eluted with the target analyte. In crop sample analysis using LC–MS/MS, the matrix effect can affect the quantification results. Chinese chives are likely to exhibit a strong matrix effect when co-extracted with bifenthrin and butachlor due to the presence of phytochemicals and chlorophyll. A novel analytical method was developed to reduce the matrix effects of bifenthrin and butachlor to a negligible level in Chinese chives. The established method had a limit of quantitation of 0.005 mg/kg and correlation coefficients greater than 0.999 within the range of 0.005–0.5 mg/kg. Matrix effects were found to be negligible, with values ranging from −18.8% to 7.2% in four different sources of chives and two leafy vegetables. Compared to conventional analytical methods for the LOQ and matrix effect, the established method demonstrated improved performances. The analytical method was further applied in a residual study in chive fields. The active ingredient of butachlor 5 granule (GR) was not detected after soil admixture application, while that of bifenthrin 1 emulsifiable concentrate (EC) showed a range from 1.002 to 0.087 mg/kg after foliar spraying. The dissipation rate constant (k) of bifenthrin was determined to be 0.115, thus its half-life was calculated to be 6.0 days. From the results, PHI and safety use standards of both pesticides were suggested. The developed analytical method can be applied to accurately determine bifenthrin and butachlor residues in Chinese chives and provides a foundation for further research on the fate and behavior of these pesticides in the environment.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

LC-MS/MS Method Minimizing Matrix Effect for the Analysis of Bifenthrin and Butachlor in Chinese Chives and Its Application for Residual Study

Kim

Lee

Jeong

et al. 2023

Foods

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“…The GC-MS/MS conditions were modified from the instrumental methodology of Park et al (2022) [24]. Pesticide multiresidues were analyzed on an Agilent 7890 B gas chromatograph system coupled with an Agilent 7000C triple quadrupole mass spectrometer (Agilent Technologies, Santa Clara, CA, USA).…”

Section: Gc-ms/ms Parametersmentioning

confidence: 99%

“…Lee et al (2017) also reported that 0.1% formic acid in ACN exhibited better recovery rates for 360 GC-MS/MS amenable pesticides in brown rice than 1% formic acid or 0.1-1% acetic acid [26]. Recently, 0.1% formic acid in ACN has been selected as an alternative extraction solvent for QuEChERS procedures in crops [31], edible insects (mealworms) [18], and biological samples [24]. Our study confirmed that 0.1% formic acid was also effective in the ACN/EA (7:3, v/v) solvent for extracting multiple residues in root/rhizome-based herbal medicines.…”

Section: Plos Onementioning

confidence: 99%

Simultaneous analytical method for 296 pesticide multiresidues in root and rhizome based herbal medicines with GC-MS/MS

2023

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A method for the simultaneous analysis of pesticide multiresidues in three root/rhizome-based herbal medicines (Cnidium officinale, Rehmannia glutinosa, and Paeonia lactiflora) was developed with GC-MS/MS. To determine the concentrations of pesticide residues, 5 g of dried samples were saturated with distilled water, extracted with 10 mL of 0.1% formic acid in acetonitrile/ethyl acetate (7:3, v/v), and then partitioned using magnesium sulfate and sodium chloride. The organic layer was purified with Oasis PRiME HLB plus light, followed by a cleanup with dispersive solid-phase extraction containing alumina. The sample was then injected into GC-MS/MS (2 μL) using a pulsed injection mode at 15 psi and analyzed using multiple reaction monitoring (MRM) modes. The limit of quantitation for the 296 target pesticides was within 0.002–0.05 mg/kg. Among them, 77.7–88.5% showed recoveries between 70% and 120% with relative standard deviations (RSDs) ≤20% at fortified levels of 0.01, and 0.05 mg/kg. The analytical method was successfully applied to real herbal samples obtained from commercial markets, and 10 pesticides were quantitatively determined from these samples.

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“…Conventional analytical techniques, such as enzyme-linked immunosorbent assays (ELISAs), 8 high-performance liquid chromatography (HPLC), 9 gas chromatography-mass spectrometry (GC-MS), 10 liquid-chromatography-mass spectrometry (LC-MS), 11 surface enhanced Raman spectrometry, 12 and metal-organic frameworks, 13 are sensitive and accurate, and are used routinely for the quantification of toxicants in water or food. However, it requires time-consuming sample preparation and relies upon sophisticated instruments and skilled manpower, requiring the transportation of samples to the laboratory for analysis.…”

Section: Introductionmentioning

confidence: 99%

Cation–π-induced mixed-matrix nanocomposite for the detection and removal of Hg²⁺ and azinphos-methyl towards environment remediation

Kaur,

Singh,

Kaur

et al. 2024

Environ. Sci.: Water Res. Technol.

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Simple and rapid method for 336 multiresidual pesticide analysis in saliva, determination of their chemical stabilities, and biomonitoring of farmers

Cited by 8 publications

References 44 publications

LC-MS/MS Method Minimizing Matrix Effect for the Analysis of Bifenthrin and Butachlor in Chinese Chives and Its Application for Residual Study

LC-MS/MS Method Minimizing Matrix Effect for the Analysis of Bifenthrin and Butachlor in Chinese Chives and Its Application for Residual Study

Simultaneous analytical method for 296 pesticide multiresidues in root and rhizome based herbal medicines with GC-MS/MS

Cation–π-induced mixed-matrix nanocomposite for the detection and removal of Hg²⁺ and azinphos-methyl towards environment remediation

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Simple and rapid method for 336 multiresidual pesticide analysis in saliva, determination of their chemical stabilities, and biomonitoring of farmers

Cited by 8 publications

References 44 publications

LC-MS/MS Method Minimizing Matrix Effect for the Analysis of Bifenthrin and Butachlor in Chinese Chives and Its Application for Residual Study

LC-MS/MS Method Minimizing Matrix Effect for the Analysis of Bifenthrin and Butachlor in Chinese Chives and Its Application for Residual Study

Simultaneous analytical method for 296 pesticide multiresidues in root and rhizome based herbal medicines with GC-MS/MS

Cation–π-induced mixed-matrix nanocomposite for the detection and removal of Hg2+ and azinphos-methyl towards environment remediation

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Product

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Cation–π-induced mixed-matrix nanocomposite for the detection and removal of Hg²⁺ and azinphos-methyl towards environment remediation