Silver nanoparticles-quercetin conjugation to siRNA against drug-resistant Bacillus subtilis for effective gene silencing: in vitro and in vivo

Sun, Dongdong; Zhang, Weiwei; Li, Nuan; Zhao, Zhiwei; Mou, Zhipeng; Yang, En-hui; Wang, Weiyun

doi:10.1016/j.msec.2016.03.024

Cited by 48 publications

(33 citation statements)

References 49 publications

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“…23 Moreover, several studies indicated that heavy metal ion such as Ag and Cu may cause potential inuence on mouse organs. 24,25 Based on the above reasons, CCM-MSNs@PVP nanobers would be potential candidate hemostatic materials for wound healing applications.…”

Section: In Vitro Antibacterial Activitymentioning

confidence: 99%

Fabrication of curcumin-loaded mesoporous silica incorporated polyvinyl pyrrolidone nanofibers for rapid hemostasis and antibacterial treatment

Nie

Chen

et al. 2017

RSC Adv.

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Section: In Vitro Antibacterial Activitymentioning

confidence: 99%

Fabrication of curcumin-loaded mesoporous silica incorporated polyvinyl pyrrolidone nanofibers for rapid hemostasis and antibacterial treatment

Nie

Chen

et al. 2017

RSC Adv.

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“…The fungal suspension was washed twice in PBS and placed on a microscope slide containing 5 μl of the different species of fungal suspensions (all samples observed within 1 hr). The normal channel of the fungus and the PI of the red channel were observed under a fluorescence microscope (Sun, Zhang et al, ).…”

Section: Methodsmentioning

confidence: 99%

Chitosan–catechin coating as an antifungal and preservable agent for postharvest satsuma oranges

et al. 2019

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The antifungal properties of chitosan–catechin coating and the effect of fruit preservation were studied. We used catechin to modify chitosan to prepare a coating. The purpose of the study was to use chitosan–catechin coating to prolong the preservation time of satsuma oranges. In vitro experiments, the results showed that the antifungal activity of chitosan–catechin increased with increasing concentration, and the results are also significantly effect of comparing to chitosan and catechin alone (*p < 0.05). In vivo studies, chitosan–catechin coating treatment significantly reduced rot caused by Penicillium Citrinum and Aspergillus niger. The physiological and biochemical indexes of the chitosan–catechin coating treatment group were significantly higher than those of the control group (*p ≤ 0.05). In the toxicity test, mice injected with chitosan–catechin solution showed no significant difference compared to the control group. These results indicate that this chitosan–catechin coating may be useful as an antifungal and preserving agent for satsuma oranges. Practical applications The fruit after harvest every year is a large loss due to improper storage, and the preservation of fruits is an effective way to reduce losses. The traditional fruit wrap is not degradable, and the preservation effect is relatively general. The chitosan film is a new type of edible fruit wrap, which has the advantages of being edible and easily degradable, and can effectively reduce environmental pollution. Adding catechin to the preparation process of chitosan film can better improve the fresh‐keeping effect and prolong the preservation time of the fruit.

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“…Silver nanoparticles were found to have an impressive inhibiting effect on human pathogens (Aeromonas hydrophila, Bacillus spp., Escherichia coli, (enteropathogenic-EP), Klebsiella spp., Salmonella spp., Salmonella paratyphi, Shigella dysenteriae, and Shigella sonnei) as well as a cytotoxic effect against human lung cancer A549 cell line [33]. Sun et al prepared fabricated silver nanoparticles combined with quercetin, which were stabilized by using a layer of molecules, that is, siRNA, and found that the prepared silver nanoparticles have potential activity against B. subtilis [34]. Li et al synthesized silver nanoparticles by reduction of aqueous silver ion with culture DOI: http://dx.doi.org/10.5772/intechopen.88684 supernatants of Aspergillus terreus, and prepared silver nanoparticles showed excellent antimicrobial activity against Candida albicans, Candida krusei, Candida parapsilosis, Candida tropicalis, Aspergillus flavus, Aspergillus fumigatus, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli [35].…”

Section: Biological Applicationsmentioning

confidence: 99%

Biological and Physical Applications of Silver Nanoparticles with Emerging Trends of Green Synthesis

Singh¹,

Κaur²

2020

Engineered Nanomaterials - Health and Safety

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Among the emerging nanotechnology, nanoparticles get much attention due to their unique physicochemical, optical, electrical, and thermal activities. Nowadays, extensive research on silver nanoparticles is going on due to their wide applicability in different fields. Silver nanoparticles possess excellent anticancer as well as antimicrobial efficacy (hence found major and wide applications as antimicrobial, wound healing, antidiarrheal, and antifungal agents). A huge and advanced perspective of silver nanoparticles is found in environmental hygiene and sterilization due to their magnificent disinfectant properties. The other major applications of silver nanoparticles include diagnostic (as biological tags in biosensors, assays, and quantitative detection), conductive (in conductive inks, pastes, and fillers), optical (metal-enhanced fluorescence and surface-enhanced Raman scattering), and household (pesticides and wastewater treatment) applications. The present review consists of an exhaustive detail about the biological and physical applications of silver nanoparticles along with the analysis of historical evolution, the present scenario, and possible future outcomes.

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Silver nanoparticles-quercetin conjugation to siRNA against drug-resistant Bacillus subtilis for effective gene silencing: in vitro and in vivo

Cited by 48 publications

References 49 publications

Fabrication of curcumin-loaded mesoporous silica incorporated polyvinyl pyrrolidone nanofibers for rapid hemostasis and antibacterial treatment

Fabrication of curcumin-loaded mesoporous silica incorporated polyvinyl pyrrolidone nanofibers for rapid hemostasis and antibacterial treatment

Chitosan–catechin coating as an antifungal and preservable agent for postharvest satsuma oranges

Biological and Physical Applications of Silver Nanoparticles with Emerging Trends of Green Synthesis

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