Silica-Supported TEMPO Catalysts:  Synthesis and Application in the Anelli Oxidation of Alcohols

Abstract

The application of silica-supported TEMPO as a recyclable catalyst in the Anelli oxidation of alcohols is reported. The catalyst is easily obtained in a one-step reductive amination procedure starting from a commercially available aminopropyl-functionalized silica. Details of the synthesis of the supported catalyst and its analysis by MAS NMR are presented. Various alcohol oxidations according to the Anelli protocol have been carried out and the stability of the applied silica-supported TEMPO has been studied.

Oxidation of Cyclohexanol on Phosphotungstic Acid Anion Intercalated Layered Double Hydroxides With Aqueous H2o2 as Oxidant

“…Furthermore, the major d(003) spacings of Mg 2 AlNi-POM LDH and Mg 3 Al-POM LDH demonstrate a higher value. The d(003) spacing of LDH-POM includes the thickness of LDH host and the gallery height of interlayer region.…”

“…[1][2][3] Oxidation of alcohols has traditionally been the major route for the preparation of carbonyl compounds. However, many of the traditional inorganic oxidants utilized for the oxidation of alcohols are hazardous or toxic, for example Na 2 Cr 2 O 7 , NaClO 4 and KMnO 4 .…”

Synthesis of TEMPO Functionalized Polyimides by A2 + B3 polymerization

“…It is also used as a radical scavenger in various chemical reactions. TEMPO is typically used in homogeneous systems, but the immobilization of TEMPO onto solid supports such as polystyrene [3] and silica [4] has also been developed. As polyimides are more thermally stable than polystyrene and more flexible than silica, the development of TEMPO functionalized polyimides will exhibit quite promising results.…”

Synthesis, Characterization of Cellulose Grafted N-Oxide Reagent and Its Application in Oxidation of Alkyl/Aryl Halides

“…To solve this problem, TEMPO residue has been successfully immobilized to polymeric supports both inorganic [8] and organic polymers [9], affording heterogeneous catalysts which are readily separated from the reaction mixtures but are usually far less versatile than the homogeneous TEMPO [10]. The use of heterogeneous catalysts in the liquid phase, however, offers several advantages over homogeneous ones, such as ease of recovery and recycling, atom utility and enhanced stability [11].…”