volume 65, issue 12, P1565-1571 2006
DOI: 10.1136/ard.2005.051086
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C Dorph, P Englund, I Nennesmo, I E Lundberg

Abstract: Objectives: To determine whether muscle weakness is correlated with inflammation, expression of interleukin 1a (IL1a) and major histocompatibility complex (MHC) class I and II antigens on muscle fibres. Methods: Biopsy specimens from clinically symptomatic (proximal muscles) and asymptomatic (all distal but two proximal) muscles in eight patients with polymyositis, three patients with dermatomyositis and six healthy controls were analysed by immunohistochemistry for the presence of T cells and macrophages, an…

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