Short-term Results of a Magnetic Resonance Imaging–Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer

Chiaro, Marco Del; Verbeke, Caroline S.; Kartalis, Nikolaos; Pozzi-Mucelli, R.; Gustafsson, Peter; Hansson, Johan; Haas, Stephan; Segersvärd, Ralf; Andrén‐Sandberg, Åke; Löhr, Matthias

doi:10.1001/jamasurg.2014.3852

Cited by 86 publications

(60 citation statements)

References 33 publications

(25 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…as magnetic resonance imaging, should be performed. 27,28 Several studies have shown that elevated ALP is a common marker for diagnosing gallstone-induced pancreatitis. 16,18 Several recent reports proposed that the ALT level might be a marker for early recognition of a gallstone etiology in patients with AP.…”

Section: 2412mentioning

confidence: 99%

The Etiologic Evaluation of Acute Pancreatitis in a General Hospital of Seoul-Gyeonggi Province in Korea

Youn

Chung

Lee

et al. 2017

Korean J Gastroenterol

View full text Add to dashboard Cite

Background/Aims: In recent years, the incidence of acute pancreatitis (AP) has been increasing. A better understanding of the etiology is directly linked to more favorable outcomes. Unfortunately, there have been reports suggesting the variation of etiologies of AP across countries. The objective of this study was to determine the etiology of AP in a general hospital of Seoul-Gyeonggi province in Korea during the past decade. Methods: We retrospectively reviewed the medical records of consecutive patients with AP who were admitted to St. Paul's Hospital (Seoul, Korea) with an affiliation to the Catholic University of Korea between January 2003 and January 2013. Results: A total of 1,110 patients were enrolled, totaling 1,833 attacks, and the most frequent cause of AP was alcohol consumption. The recurrence rate of AP was 24.5% (272/1,110), and habitual recurrence rate (more than three times) was 12.6% (140/1,110). The rate of severe AP was 4.9% (90/1,833 attacks). The mortality rate of AP was 2.6% (29/1,110 patients). The frequency of an idiopathic cause of AP was 13.3%. The recurrence rate and mortality rate of idiopathic AP were 16.2% and 5.4%, respectively. In 41.7% (10/24) of cases of idiopathic AP, microlithiasis was suspected. Conclusions: Between 2003 and 2013 in Korea, alcohol was the most frequent cause of AP in the general hospital of Seoul-Gyeonggi province of Korea. It appears that alcohol abstinence program may be necessary. Further nationwide studies would be needed to evaluate the etiologies of AP. (Korean J Gastroenterol 2017;70:190-197)

show abstract

Section: 2412mentioning

confidence: 99%

The Etiologic Evaluation of Acute Pancreatitis in a General Hospital of Seoul-Gyeonggi Province in Korea

Youn

Chung

Lee

et al. 2017

Korean J Gastroenterol

View full text Add to dashboard Cite

show abstract

“…Additionally, the results of 3 large cohort studies have been released since Lu's publication. 7,10,11 This study aims to estimate the diagnostic yield of abdominal imaging for pancreatic cancer screening in HRI based on existing literature. We estimated detection rates of high-risk lesions using 2 different imaging strategies (EUS or MRI) and compared imaging findings among different HRI groups.…”

mentioning

confidence: 99%

Diagnostic Yield From Screening Asymptomatic Individuals at High Risk for Pancreatic Cancer: A Meta-analysis of Cohort Studies

Corral

Mareth

Riegert–Johnson

et al. 2019

Clinical Gastroenterology and Hepatology

View full text Add to dashboard Cite

show abstract

“…104 A recent Swiss study of MR-based pancreatic cancer screening in high-risk individuals similarly detected pancreatic lesions in 40% of individuals. 105 Within this study, 12.5% of patients underwent pancreatic resection due to abnormalities seen on screening, and 7.5% of the cohort was found to have resectable adenocarcinoma. 105 …”

Section: Hereditary/familial Pancreatic Cancermentioning

confidence: 78%

“…105 Within this study, 12.5% of patients underwent pancreatic resection due to abnormalities seen on screening, and 7.5% of the cohort was found to have resectable adenocarcinoma. 105 …”

Section: Hereditary/familial Pancreatic Cancermentioning

confidence: 78%

Advances in Hereditary Colorectal and Pancreatic Cancers

Underhill

Germansky

Yurgelun

2016

Clinical Therapeutics

View full text Add to dashboard Cite

Purpose Innovations in genetic medicine have lead to improvements in the early detection, prevention, and treatment of cancer for patients with inherited risks of gastrointestinal cancer, particularly hereditary colorectal cancer and hereditary pancreatic cancer. Methods This review provides an update on recent data and key advances that have improved the identification, understanding, and management of patients with hereditary colorectal cancer and hereditary pancreatic cancer. Findings This review details recent and emerging data that highlight the developing landscape of genetics in hereditary colorectal and pancreatic cancer risk. A summary is provided of the current state-of-the-art practices for identifying, evaluating, and managing patients with suspected hereditary colorectal cancer and pancreatic cancer risk. The impact of next-generation sequencing technologies in the clinical diagnosis of hereditary gastrointestinal cancer and also in discovery efforts of novel genes linked to familial cancer risk are discussed. Emerging targeted therapies that may play a particularly important role in the treatment of patients with hereditary forms of colorectal cancer and pancreatic cancer are also reviewed. Current approaches for pancreatic cancer screening and the psychosocial impact of such procedures are also detailed. Implications Given the availability of novel diagnostic, risk-reducing, and therapeutic strategies that exist for patients with hereditary risk for colorectal or pancreatic cancer, it is imperative that clinicians be vigilant about evaluating patients for hereditary cancer syndromes. Continuing to advance genetics research in hereditary gastrointestinal cancers will allow for more progress to be made in personalized medicine and prevention.

show abstract

Short-term Results of a Magnetic Resonance Imaging–Based Swedish Screening Program for Individuals at Risk for Pancreatic Cancer

Abstract: During a median follow-up of approximately 1 year, pancreatic lesions were detected in 40% of the patients, of whom 5 underwent surgery. Although the study time was relatively short, the surveillance program in individuals at risk seems to be effective.

Cited by 86 publications

References 33 publications

The Etiologic Evaluation of Acute Pancreatitis in a General Hospital of Seoul-Gyeonggi Province in Korea

The Etiologic Evaluation of Acute Pancreatitis in a General Hospital of Seoul-Gyeonggi Province in Korea

Diagnostic Yield From Screening Asymptomatic Individuals at High Risk for Pancreatic Cancer: A Meta-analysis of Cohort Studies

Advances in Hereditary Colorectal and Pancreatic Cancers

Contact Info

Product

Resources

About