Short-term exposure to hydrogen peroxide induces mortality and alters exploratory behaviour of European lobster (Homarus gammarus)

Escobar-Lux, Rosa H.; Parsons, Aoife E.; Samuelsen, Ole Bent; Agnalt, Ann‐Lisbeth

doi:10.1016/j.ecoenv.2020.111111

Cited by 8 publications

(2 citation statements)

References 32 publications

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“…The half‐life of H 2 O 2 is rather long in seawater and can range from 7 days at 15°C to 28 days when environmental parameters vary 107 . Consequently, residues of H 2 O 2 in the water column can be toxic for several non‐target taxa including crustaceans harbouring the vicinity of salmon farms such as the European lobster ( Homarus gammarus ), 108 copepods ( Acartia hudsonica ), 109 polychaetes ( Capitella sp. and Ophryotrocha spp.…”

Section: Antiparasitic Treatments In Mediterranean Aquaculture: Deliv...mentioning

confidence: 99%

Antiparasitic approaches and strategies in European aquaculture, with emphasis on Mediterranean marine finfish farming: Present scenarios and future visions

Rigos,

Padrós,

Golomazou

et al. 2023

Reviews in Aquaculture

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Parasitic infections can be occasionally severe in the European marine aquaculture industry, including the Mediterranean region, as they can incur considerable financial losses. Due to the lack of commercial vaccines, therapeutic approaches seem the only measure to battle parasitic outbreaks. Integrated strategies and increased resilience of the hosts, may limit to some degree the level of infestation. Ectoparasitic therapy is traditionally based on baths, with few exceptions. Several antiparasitic compounds have been registered in European aquatic medicine to combat mainly salmon sea lice; however, few of them are readily used against Mediterranean fish parasites. Formalin and less commonly hydrogen peroxide baths are applied against ectoparasites in the Mediterranean region. Most of the registered anti‐lice antiparasitics have limited potential perhaps due to their adverse environmental impact. Future therapies against fish parasites will rely mainly on effective substances ensuring consumer, animal, and environmental welfare. Ideally, dietary antiparasitics such as praziquantel exhibiting mild environmental impact and high efficacy against a wide range of pathogens should be adopted. Moreover, combined strategies such as integrated pest management, involving various management practices with limited use of chemicals, should be a priority for specific parasitic outbreaks. The information presented in this review can guide future research and promote effective and prudent parasite control practices for Mediterranean‐farmed fish.

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Section: Antiparasitic Treatments In Mediterranean Aquaculture: Deliv...mentioning

confidence: 99%

Antiparasitic approaches and strategies in European aquaculture, with emphasis on Mediterranean marine finfish farming: Present scenarios and future visions

Rigos,

Padrós,

Golomazou

et al. 2023

Reviews in Aquaculture

View full text Add to dashboard Cite

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“…They are pivotal organisms in the maintenance of ecological balance in the marine ecosystem and are found in all marine environments [ 25 , 26 ]. European lobsters at pelagic larvae stage [ 27 ], deep-water shrimp [ 8 ], zooplankton [ 28 ], and krill [ 29 ] have all been observed to suffer adverse behavioural and genotoxic effects, when exposed to 10–1000 times dilutions (53–5.3 mM) of the recommended sea lice treatment, and sublethal behavioural changes observed at 100–200 times dilutions (265–530 µM). It is unknown how sea urchin coelomocytes will respond to realistic environmental concentrations of H 2 O 2 , however their role as a benthic bioindicator species [ 30 ], along with their ease of collection, maintenance, husbandry, cell extraction, transparency and large quantities of embryos, and larvae, make them an ideal model for investigating H 2 O 2 impacts.…”

Section: Introductionmentioning

confidence: 99%

Interspecific differences in oxidative DNA damage after hydrogen peroxide exposure of sea urchin coelomocytes

et al. 2022

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Interspecific comparison of DNA damage can provide information on the relative vulnerability of marine organisms to toxicants that induce oxidative genotoxicity. Hydrogen peroxide (H2O2) is an oxidative toxicant that causes DNA strand breaks and nucleotide oxidation and is used in multiple industries including Atlantic salmon aquaculture to treat infestations of ectoparasitic sea lice. H2O2 (up to 100 mM) can be released into the water after sea lice treatment, with potential consequences of exposure in nontarget marine organisms. The objective of the current study was to measure and compare differences in levels of H2O2-induced oxidative DNA damage in coelomocytes from Scottish sea urchins Echinus esculentus, Paracentrotus lividus, and Psammechinus miliaris. Coelomocytes were exposed to H2O2 (0–50 mM) for 10 min, cell concentration and viability were quantified, and DNA damage was measured by the fast micromethod, an alkaline unwinding DNA method, and the modified fast micromethod with nucleotide-specific enzymes. Cell viability was >92% in all exposures and did not differ from controls. Psammechinus miliaris coelomocytes had the highest oxidative DNA damage with 0.07 ± 0.01, 0.08 ± 0.01, and 0.07 ± 0.01 strand scission factors (mean ± SD) after incubation with phosphate-buffered saline, formamidopyrimidine-DNA glycosylase, and endonuclease-III, respectively, at 50 mM H2O2. Exposures to 0.5 mM H2O2 (100-fold dilution from recommended lice treatment concentration) induced oxidative DNA damage in all three species of sea urchins, suggesting interspecific differences in vulnerabilities to DNA damage and/or DNA repair mechanisms. Understanding impacts of environmental genotoxicants requires understanding species-specific susceptibilities to DNA damage, which can impact long-term stability in sea urchin populations in proximity to aquaculture farms.

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The Acute and Delayed Mortality of the Northern Krill (Meganyctiphanes norvegica) When Exposed to Hydrogen Peroxide

Escobar-Lux

Samuelsen

2020

Bull Environ Contam Toxicol

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Bath treatment pharmaceuticals used to control sea lice infestations in the salmonid industry, such as hydrogen peroxide (H2O2), are released directly into the environment where non-target organisms are at risk of exposure. The aim of this study was to determine the threshold concentrations for mortality of the Northern krill, Meganyctiphanes norvegica, a major component of the north Atlantic marine ecosystem. To assess the lethal effects of H2O2, we carried out a series of 1 h acute toxicity tests and assessed mortality through a 48 h post-exposure period. One-hour exposure to 170 mg/L, corresponding to 10% of the recommended H2O2 treatment, caused 100% mortality and a subsequent acute median-lethal concentration LC50 value of 32.5 mg/L. Increased mortality was observed with time in all exposed groups, resulting in successively lower LC50 values during the post-exposure period. The suggested H2O2 concentrations have the potential of causing negative effects to the Northern krill.

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Short-term exposure to hydrogen peroxide induces mortality and alters exploratory behaviour of European lobster (Homarus gammarus)

Cited by 8 publications

References 32 publications

Antiparasitic approaches and strategies in European aquaculture, with emphasis on Mediterranean marine finfish farming: Present scenarios and future visions

Antiparasitic approaches and strategies in European aquaculture, with emphasis on Mediterranean marine finfish farming: Present scenarios and future visions

Interspecific differences in oxidative DNA damage after hydrogen peroxide exposure of sea urchin coelomocytes

The Acute and Delayed Mortality of the Northern Krill (Meganyctiphanes norvegica) When Exposed to Hydrogen Peroxide

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