Short-course antibiotics for acute otitis media

Abstract

Trusted evidence. Informed decisions. Better health.

Diagnosis, Microbial Epidemiology, and Antibiotic Treatment of Acute Otitis Media in Children

“…Using this definition, we can conclude equivalence for 2 of the 8 pooled analyses in eTable 2 and that effects are inconclusive for the remaining 6. The MCID has important implications for our conclusions; for example, in contrast to a previous systematic review, 7 we are unable to make definitive conclusions regarding the equivalency of short-vs long-term regimens analyzed by antibiotic when considering an MCID of 5%, except for 7 to 10 days of cefaclor vs 3 days of azithromycin.…”

Diagnosis, Microbial Epidemiology, and Antibiotic Treatment of Acute Otitis Media in Children

“…Using this definition, we can conclude equivalence for 2 of the 8 pooled analyses in eTable 2 and that effects are inconclusive for the remaining 6. The MCID has important implications for our conclusions; for example, in contrast to a previous systematic review, 7 we are unable to make definitive conclusions regarding the equivalency of short-vs long-term regimens analyzed by antibiotic when considering an MCID of 5%, except for 7 to 10 days of cefaclor vs 3 days of azithromycin.…”

Beyond antibiotic prescribing rates: first-line antibiotic selection, prescription duration, and associated factors for respiratory encounters in urgent care

“…Both MD/DO and APC providers participate equally in education and tracking efforts and receive the same academic detailing communications. Recent data suggest shorter courses of therapy are sufficient for sinusitis and AOM in certain situations, 10 , 35 and our findings emphasize the opportunity to improve the duration of antibiotic prescriptions among all clinicians.…”

Short-term antibiotic therapy for the most common bacterial respiratory infections in infants and children

“…However, results of a meta-analysis of 49 trials including 12,045 participants could lead to different conclusions and suggest a preference for long-term therapy. In this study administration of antibiotics for 5 days was associated with a slight but significant ly increased risk of failure (21% vs. 18%; OR 1.34, 95% CI 1.15–1.55) at 1 month initiation of therapy ( Kozyrskyj et al, 2010 ).…”

Diagnosis, Microbial Epidemiology, and Antibiotic Treatment of Acute Otitis Media in Children

“…Using this definition, we can conclude equivalence for 2 of the 8 pooled analyses in eTable 2 and that effects are inconclusive for the remaining 6. The MCID has important implications for our conclusions; for example, in contrast to a previous systematic review, 7 we are unable to make definitive conclusions regarding the equivalency of short-vs long-term regimens analyzed by antibiotic when considering an MCID of 5%, except for 7 to 10 days of cefaclor vs 3 days of azithromycin.…”

Beyond antibiotic prescribing rates: first-line antibiotic selection, prescription duration, and associated factors for respiratory encounters in urgent care

“…Both MD/DO and APC providers participate equally in education and tracking efforts and receive the same academic detailing communications. Recent data suggest shorter courses of therapy are sufficient for sinusitis and AOM in certain situations, 10 , 35 and our findings emphasize the opportunity to improve the duration of antibiotic prescriptions among all clinicians.…”

Short-term antibiotic therapy for the most common bacterial respiratory infections in infants and children

“…However, results of a meta-analysis of 49 trials including 12,045 participants could lead to different conclusions and suggest a preference for long-term therapy. In this study administration of antibiotics for 5 days was associated with a slight but significant ly increased risk of failure (21% vs. 18%; OR 1.34, 95% CI 1.15–1.55) at 1 month initiation of therapy ( Kozyrskyj et al, 2010 ).…”

Diagnosis, Microbial Epidemiology, and Antibiotic Treatment of Acute Otitis Media in Children

“…Using this definition, we can conclude equivalence for 2 of the 8 pooled analyses in eTable 2 and that effects are inconclusive for the remaining 6. The MCID has important implications for our conclusions; for example, in contrast to a previous systematic review, 7 we are unable to make definitive conclusions regarding the equivalency of short-vs long-term regimens analyzed by antibiotic when considering an MCID of 5%, except for 7 to 10 days of cefaclor vs 3 days of azithromycin.…”

Beyond antibiotic prescribing rates: first-line antibiotic selection, prescription duration, and associated factors for respiratory encounters in urgent care

“…Both MD/DO and APC providers participate equally in education and tracking efforts and receive the same academic detailing communications. Recent data suggest shorter courses of therapy are sufficient for sinusitis and AOM in certain situations, 10 , 35 and our findings emphasize the opportunity to improve the duration of antibiotic prescriptions among all clinicians.…”

Short-term antibiotic therapy for the most common bacterial respiratory infections in infants and children

“…However, results of a meta-analysis of 49 trials including 12,045 participants could lead to different conclusions and suggest a preference for long-term therapy. In this study administration of antibiotics for 5 days was associated with a slight but significant ly increased risk of failure (21% vs. 18%; OR 1.34, 95% CI 1.15–1.55) at 1 month initiation of therapy ( Kozyrskyj et al, 2010 ).…”