volume 16, issue 10, P1064-1068 1997
DOI: 10.1076/ceyr.16.10.1064.9017
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Abstract: The present study supports the contention that TNF-alpha is a major mediator of AIDS-associated optic neuropathy. HIV infection induces the production of TNF-alpha in macrophages and astrocytes, which probably causes demyelination and other neuronal damage.