“…In fact, the present results could have been obtained from eyeblinks emanating from startle or nociceptive circuitry, because a similar pattern of modulation has been observed for startle eyeblinks evoked by non-noxious acoustic stimuli Cuthbert et al, 1996;Lang et al, 1997) and reactions that are nociceptive in origin (pain, NFR) (Rhudy et al, 2005(Rhudy et al, , 2006(Rhudy et al, , 2007a. Furthermore, startle and nociception may be modulated by a common circuit (e.g., amygdala & PAG) (Crown et al, 2000;Davis, 1997;Fanselow, 1994;Fendt et al, 1994;Lang and Davis, 2006;Manning and Mayer, 1995;McLemore et al, 1999). Although additional research is needed to address this issue, our data suggest eyeblinks elicited by noxious electric stimulation of the sural nerve do not habituate as quickly as eyeblinks elicited by acoustic startle probes or electrical probes delivered to the arm.…”