Shining New Light on an Old Problem: Retooling MALDI Mass Spectrometry for Organotransition‐Metal Catalysis

Theory meets experiment: Gas-phase chemistry of coinage metals

“…Despite the indirect experimental evidence for the involvement of copper(III) intermediates in this reaction, it remains to be shown, whether copper(III) really plays a role or if metal clusters which would circumvent Cu III are involved. In this respect, the effective and non-destructive ionization of sensitive organometallic reagents such as organocuprates remains a challenge for future instrumental development, and some recent results appear quite promising in this respect [156].…”

Room temperature aerobic oxidation of alcohols using CuBr2 with TEMPO and a tetradentate polymer based pyridyl-imine ligand

“…We monitored the metal-centred reaction process by MALDI-TOF mass spectrometry using L2 as an example. MALDI-TOF mass spectrometry is developing as a useful method for probing metal-centred reactions, especially when the paramagnetic nature of a metal centre thwarts NMR based methods of interrogation [63][64]. An aliquot of the reaction mixture was mixed with matrix (dithranol) and the solution was spotted onto the MALDI plate and allowed to evaporate.…”

Zinc Complexes of Piperazinyl‐Derived Aminephenolate Ligands: Synthesis, Characterization and Ring–Opening Polymerization Activity

“…Anthracene was used as the matrix for ligands and complexes. [59][60] Mass spectra were also obtained by AP-CI MS in positive mode (70 eV) using an Agilent 1100 LC mass spectrometer. GPC data were collected on a Viscotek GPCMax System equipped with a Refractive Index Detector and columns purchased from Phenomenex (Phenogel 5 µ Linear/mixed bed 300 × 4.60 mm column in series with a Phenogel 5 µ 100 Å 300 × 4.60 mm column).…”