Abstract:Supramolecular self‐assembly of polymeric molecules for sharp‐pH‐sensitive (SPS) nanoparticles is an especially important application in biology. Here, amphiphilic polypeptide copolymers are synthesized and spontaneously assembled to micelles in aqueous solution, and protonation of the tertiary amine groups in the side‐chain of the copolymer under weak acid causes the micelle disassembly, which is sharp‐pH‐sensitive, and the responsive pHs can be adjusted by adding salts. Size and morphologic change of the pol… Show more
Oxygen self-sufficient fluorinated polypeptide nanoparticles have been synthesized via the loading of a NIR photosensitizer (BODIPY-Br2) into a water-dispersible drug delivery system for high efficiency PDT.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.