PLoS ONE volume 9, issue 6, Pe98456 2014 DOI: 10.1371/journal.pone.0098456 View full text
Jedrzej Hoffmann, Manuel Ospelt, Christian Troidl, Sandra Voss, Christoph Liebetrau, Won-Keun Kim, Andreas Rolf, Astrid Wietelmann, Thomas Braun, Kerstin Troidl, Sakthivel Sadayappan, David Barefield, Christian Hamm, Holger Nef et al.

Abstract: AimsMouse models of myocardial infarction (MI) are commonly used to explore the pathophysiological role of the monocytic response in myocardial injury and to develop translational strategies. However, no study thus far has examined the potential impact of inter-individual variability and sham surgical procedures on monocyte subset kinetics after experimental MI in mice. Our goal was to investigate determinants of systemic myeloid cell subset shifts in C57BL/6 mice following MI by developing a protocol for sequ…

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