Sex differences in leadless pacemaker implantation: A propensity-matched analysis from the i-LEAPER registry

Mitacchione, Gianfranco; Schiavone, Marco; Gasperetti, Alessio; Arabia, Gianmarco; Tundo, Fabrizio; Berndt, Alexander; Montemerlo, Elisabetta; Monaco, Cinzia; Gulletta, Simone; Palmisano, Pietro; Höfer, Daniel; Rovaris, Giovanni; Russo, Antonio Dello; Biffi, Mauro; Pisanó, Ennio; Bella, Paolo Della; Biase, Luigi Di; Chierchia, Gian Battista; Saguner, Ardan M.; Tondo, Claudio; Curnis, Antonio; Forleo, Giovanni B.

doi:10.1016/j.hrthm.2023.07.061

Cited by 9 publications

(2 citation statements)

References 27 publications

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“…These factors increase the risk of bleeding and infection associated with traditional pacemakers. In this context, leadless pacemakers may be a preferable choice (14,15). Pre-existing cardiac conduction block can be used to predict the risk of PPI after TAVI.…”

Section: Discussionmentioning

confidence: 99%

Predictors of permanent pacemaker implantation in aortic valve diseases after TAVI with vitaFlow liberty system

Ju,

Xie,

Tang

et al. 2023

Front. Cardiovasc. Med.

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IntroductionPermanent pacemaker implantation (PPI) is a known complication in patients with aortic stenosis following transcatheter aortic valve implantation (TAVI). However, there is limited research on TAVI for pure aortic regurgitation (PAR), and more investigation is needed to determine the occurrence of postoperative cardiac conduction block and the need for PPI in this population. Therefore, this retrospective analysis aimed to evaluate the incidence of cardiac conduction block and the necessity of PPI after TAVI in patients with different types of aortic valve disease, including pure aortic stenosis (PAS), aortic stenosis with regurgitation (ASR), and PAR.MethodsClinical data of 100 patients who TAVI were analyzed retrospectively. The incidence of conduction block was assessed, and clinical factors were examined to predict the necessity of PPI.ResultsCardiac conduction block was found to be a common complication following TAVI, particularly in patients with PAR. PAR was identified as an independent risk factor for requiring PPI. Additionally, first-degree atrioventricular block emerged as a sensitive predictor for PPI in patients with PAR.DiscussionThese findings provide valuable insights into the safety and effectiveness of TAVI, which can help enhance patient management and reduce complications.

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Section: Discussionmentioning

confidence: 99%

Predictors of permanent pacemaker implantation in aortic valve diseases after TAVI with vitaFlow liberty system

Ju,

Xie,

Tang

et al. 2023

Front. Cardiovasc. Med.

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“…One argument is that the underrepresentation of the female sex in cardiac interventional procedures is mainly due to a perceived greater frailty of the female sex. A recent analysis on sex differences on leadless pacemaker implantation showed that men and women have the same adverse event risk in the operative and long-term setting, rebutting this argument that females are a high-risk group of patients within interventional procedures [23]. An argument for sex differences could be that the surgeons (mostly men) argue/explain risks and benefits of an operation differently to male (same sex) in comparison to females (different sex).…”

Section: Discussionmentioning

confidence: 99%

Living Longer or Better—Patient’s Choice in Cardiac Surgery Is Gender-Dependent—A Multicenter Study

Hofmann,

Rae,

Puvogel

et al. 2023

JCM

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In view of the increasing age of cardiac surgery patients, questions arise about the expected postoperative quality of life and the hoped-for prolonged life expectancy. Little is known so far about how these, respectively, are weighted by the patients concerned. This study aims to obtain information on the patients’ preferences. Between 2015 and 2017, data were analyzed from 1349 consecutive patients undergoing cardiac surgery at seven heart centers in Germany. Baseline data regarding the patient’s situation as well as a questionnaire regarding quality of life versus lifespan were taken preoperatively. Patients were divided by age into four groups: below 60, 60–70, 70–80, and above 80 years. As a result, when asked to decide between quality of life and length of life, about 60% of the male patients opted for quality of life, independent of their age. On the other hand, female patients’ preference for quality of life increased significantly with age, from 51% in the group below sixty to 76% in the group above eighty years. This finding suggests that female patients adapt their preferences with age, whereas male patients do not. This should impact further the treatment decisions of elderly patients in cardiac surgery within a shared decision-making process.

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Gender Differences With Leadless Pacemakers: Periprocedural Complications, Long-Term Device Function, and Clinical Outcomes

Huang,

Bhatia,

Lloyd

et al. 2024

The American Journal of Cardiology

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Sex differences in leadless pacemaker implantation: A propensity-matched analysis from the i-LEAPER registry

Cited by 9 publications

References 27 publications

Predictors of permanent pacemaker implantation in aortic valve diseases after TAVI with vitaFlow liberty system

Predictors of permanent pacemaker implantation in aortic valve diseases after TAVI with vitaFlow liberty system

Living Longer or Better—Patient’s Choice in Cardiac Surgery Is Gender-Dependent—A Multicenter Study

Gender Differences With Leadless Pacemakers: Periprocedural Complications, Long-Term Device Function, and Clinical Outcomes

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