Sex difference in the prevalence of metabolic syndrome and cardiovascular-related risk factors in urban adults from 33 communities of China: The CHPSNE study

Abstract

Little is known about the epidemiology of metabolic syndrome in urban areas of China. To estimate the prevalence of MetS and identify its cardiovascular-related factors in men and women, a representative sample of 15,477 urban adults aged 18-74 years in Northeast China was selected from 2009 to 2010. The diagnosis of metabolic syndrome was based on criteria set by the National Cholesterol Education Program/Adult Treatment Panel. The overall prevalence of metabolic syndrome was 27.4% (men 27.9% and women 26.8%). Multivariable logistic regression analysis revealed that a higher education level and a higher family income were associated with a higher prevalence of metabolic syndrome in men, but associated with lower prevalence of metabolic syndrome among women. Higher physical activity was associated with a decreased prevalence of metabolic syndrome in men (adjusted odds ratios (aORs) = 0.88, 95% confidence interval (CI): 0.79-0.99), but associated with an increased prevalence of metabolic syndrome in women (aOR = 1.14, 95% CI: 1.00-1.29). Compared with rice as the major staple food, cooked wheaten foods were associated with lower adjusted odds for metabolic syndrome both in men (aOR = 0.72, 95% CI: 0.58-0.90) and in women (aOR = 0.72, 95% CI: 0.56-0.92). In conclusion, metabolic syndrome is highly prevalent in urban areas of China, and there is heterogeneity by sex in the relationships between risk factors and metabolic syndrome prevalence.

Association between liver function and metabolic syndrome in Chinese men and women

“…People with MS are a susceptible population of many diseases, like type 2 diabetes and cardiovascular diseases23. Sex and age have great influence on the development of MS. MS prevalence increases during aging, but before menopause men have significantly higher MS risk than females, after menopause females have higher MS risk than males456789.…”

Clinical update on metabolic syndrome

“…However, one research 9 investigated MS prevalence in Korean population; MS was 14.3% for parents and 7.2% for offspring. Song et al 10 studied the MS prevalence in 15.477 individuals from another oriental country, China. They detected a prevalence of 27.4%.…”

Metabolic syndrome: Different definitions and gender-specific associations with cardiovascular risk factors

“…14 Previous Chinese studies 15,16 reported gender-specific correlations between SUA, MetS and CV risk factors. It would be useful to know whether there were such differences in the Song et al 1 study.…”

“…Song et al, 1 in the May 2015 issue of the journal, comment on gender differences in the associations between the prevalence of metabolic syndrome (MetS) and cardiovascular (CV) risk factors in urban adults from 33 Chinese communities.…”

“…7,[9][10][11] To help resolve these discrepancies, a Joint Interim Societies MetS definition was produced, 12 setting definitive waist circumference (WC) criteria based on ethnicity. However, Song et al 1 did not use this MetS definition, although they adjusted the WC as suggested (but not defined) in the diagnostic criteria they used. 5 Future studies should apply the same diagnostic criteria in order to facilitate comparisons.…”