Sex cord-stromal and steroid cell tumors of the ovary.

Outwater, Eric K.; Wagner, Barbara; Mannion, Ciaran; Mclarney, J. K.; Kim, Bobyun

doi:10.1148/radiographics.18.6.9821198

Cited by 225 publications

(211 citation statements)

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“…The adult form shows more variability due to cystic component and it can appear as a solid mass. Hemorrhage, necrosis and fibrinoid degeneration can result in a heterogeneous solid appearance (Outwater et al, 1998). Calcifications and papillary projections are not seen in the sonographic evaluation of these patients (Gittleman et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

Parameters for Predicting Granulosa Cell Tumor of the Ovary: A Single Center Retrospective Comparative Study

Yeşilyurt¹,

Tokmak²,

Güzel³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: To evaluate factors for predicting the granulosa cell tumor of the ovary (GCTO) pre-operatively. Materials and Methods: This retrospective designed study was conducted on 34 women with GCTO as the study group and 76 women with benign ovarian cysts as the control group. Data were recorded from the hospital database and included age, body mass index (BMI), parity, serum estradiol (E 2 ) levels, diameter of the mass, ultrasonographic features, serum CA125 level, risk of malignancy index (RMI), duration of menopause, postoperative histopathology result, and the neutrophil/lymphocyte ratio (NLR). Results: The demographic parameters showed no statistically significant difference between the groups. Preoperative diameter of the mass, CA125, duration of menopause, and neutrophil/lymphocyte ratio were significantly different between the groups. ROC curve analysis demonstrated that diameter of the mass, serum estradiol and Ca125 levels, RMI and NLR may be discriminative factors in predicting GCTO preoperatively. Conclusions: In conclusion, we think that a careful preoperative workshop including diameter of the mass, serum estradiol (E 2 ) and Ca125 levels, RMI and NLR may predict GCTO and may prevent incomplete approaches.

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Section: Discussionmentioning

confidence: 99%

Parameters for Predicting Granulosa Cell Tumor of the Ovary: A Single Center Retrospective Comparative Study

Yeşilyurt¹,

Tokmak²,

Güzel³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…It is noteworthy that abnormal uterine bleeding is not a rare presentation, even in postmenopausal women (6,19). Rarely, patients may present with abnormal uterine bleeding from endometrial hyperplasia or virilization due to the excess estrogens produced by the luteinized stroma in a malignant ovary (41,42).…”

Section: Clinical Presentationsmentioning

confidence: 99%

Metastatic gastric cancer to the female genital tract

Matsushita

Watanabe

Wakatsuki

2016

Molecular and Clinical Oncology

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Abstract. Metastases to the female genital tract from gastric cancer are rare, but they significantly worsen the prognosis of such patients. The potential routes for metastasis to the female genital tract from gastric cancer include hematogenous spread, lymphatic spread and surface implantation. The rate of lymphatic metastasis to the ovary from gastric cancer has been reported to be higher compared with that from colorectal cancer. Uterine or Fallopian tube metastases are usually secondary to ovarian metastases, which are typically identified prior to the detection of gastric cancer in half of all synchronous cases, with complaints of abdominal distention, pain, palpable mass, or abnormal uterine bleeding. The prognosis of patients with female genital tract metastases from gastric cancer is extremely poor, and is worse compared with that of other primary sites, such as the breast and colorectum. In the past, surgical intervention in such patients consisted mainly of palliative resection to relieve the symptoms associated with a sizeable pelvic mass. However, recent retrospective studies based on a relatively small number of patients have reported that surgical tumor debulking plus chemotherapy may improve the prognosis of patients with metastatic ovarian cancer originating from gastric cancer.

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“…Virilisation in a menopausal woman with a previous kidney transplant can be <1 cm in diameter. 3 In this patient, normal levels of DHEAS and 17-OHP made adrenal tumour and congenital adrenal hyperplasia unlikely. Ovarian virilising tumours have to be suspected.…”

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confidence: 75%