“…17,[23][24][25][26] The role of TSH in the pathogenesis of arthropathy was also highlighted because normalization of TSH levels under thyroid hormone substitution therapy leads to improvement and complete resolution of articular symptoms. 14,15,17,[27][28][29] However, other studies showed that rheumatic manifestations may occur in patients with chronic lymphocytic thyroiditis, even in those with TSH levels within normal ranges. 3,30,31,25,28 Besides, Le Riche et al 32 reported cases of inflammatory polyarthritis (joint stiffness, tenderness, and effusion) in patients with HT with no improvement of arthritis under thyroid replacement.…”