Severe Cutaneous Vasculitis Complicating Ulcerative Colitis

Leukocytoclastic vasculitis in an adolescent with ulcerative colitis: Report of a case and review of the literature

“…Synchronous presentation of LV and UC occurred in one patient (8%). 11–19 Of the reported patients, LV manifested during active colitis in six patients (50%) and in the absence of colitis in two patients (17%). The other four patients (33%) initially developed LV prior to any symptoms of UC, but all developed recurrent LV with subsequent onset of active colitis.…”

Leukocytoclastic vasculitis in an adolescent with ulcerative colitis: Report of a case and review of the literature

“…Synchronous presentation of LV and UC occurred in one patient (8%). 11–19 Of the reported patients, LV manifested during active colitis in six patients (50%) and in the absence of colitis in two patients (17%). The other four patients (33%) initially developed LV prior to any symptoms of UC, but all developed recurrent LV with subsequent onset of active colitis.…”

Vasculitis leucocitoclásticas como manifestación extraintestinal dermatológica rara de la enfermedad inflamatoria intestinal asociada con Clostridium: reporte de un caso

“…Su presentación clínica de vasculitis leucocitoclástica se caracteriza por púrpura palpable, con síntomas de dolor y ardor en múltiples áreas (58 %) o en un solo sitio (42 %). Sus lesiones se localizan predominantemente en las extremidades inferiores (83 %), seguidas de las extremidades superiores (42 %), el tronco (25 %) y los glúteos (25 %) (3,12,13). Ante la sospecha de vasculitis leucocitoclástica como manifestación extraintestinal dermatológica de CU, se debe realizar una biopsia cutánea para observar las características histológicas de infiltración de neutrófilos y linfocitos alrededor de los vasos sanguíneos dérmicos que muestran leucocitoclasia, depósito de fibrina en los vasos, trombos de fibrina, extravasación de eritrocitos y necrosis epidérmica resultante (10,14).…”

Cutaneous small‐vessel vasculitis associated with paediatric ulcerative colitis: A case study and literature review

“…). Using the keyword ‘ulcerative colitis’, 248 articles were found, of which 7 described the occurrence of LCV in the UC paediatric population . Using the keyword ‘Crohn's disease’, 266 papers were found.…”

“…All case reports concerning cutaneous lesions diagnosed as LCV at skin biopsy were included according to the EULAR/PRINTO/PRES classification criteria of childhood vasculitis . A summary of clinical features and treatment outcomes of 10 selected cases of LCV in paediatric patients with IBD is presented in Table . LCV occurs mostly in adolescents, with a striking female predominance of nearly 3:1.…”

“…The clinical response obtained in our case after the start of methotrexate shows that LCV can be considered an EIM of IBD. On the other hand, increasing evidence for anti‐tumour necrosis factor‐α agent efficacy in cutaneous EIMs exists …”

Leukocytoclastic vasculitis in an adolescent with ulcerative colitis: Report of a case and review of the literature

“…Synchronous presentation of LV and UC occurred in one patient (8%). 11–19 Of the reported patients, LV manifested during active colitis in six patients (50%) and in the absence of colitis in two patients (17%). The other four patients (33%) initially developed LV prior to any symptoms of UC, but all developed recurrent LV with subsequent onset of active colitis.…”

Vasculitis leucocitoclásticas como manifestación extraintestinal dermatológica rara de la enfermedad inflamatoria intestinal asociada con Clostridium: reporte de un caso

“…Su presentación clínica de vasculitis leucocitoclástica se caracteriza por púrpura palpable, con síntomas de dolor y ardor en múltiples áreas (58 %) o en un solo sitio (42 %). Sus lesiones se localizan predominantemente en las extremidades inferiores (83 %), seguidas de las extremidades superiores (42 %), el tronco (25 %) y los glúteos (25 %) (3,12,13). Ante la sospecha de vasculitis leucocitoclástica como manifestación extraintestinal dermatológica de CU, se debe realizar una biopsia cutánea para observar las características histológicas de infiltración de neutrófilos y linfocitos alrededor de los vasos sanguíneos dérmicos que muestran leucocitoclasia, depósito de fibrina en los vasos, trombos de fibrina, extravasación de eritrocitos y necrosis epidérmica resultante (10,14).…”

Cutaneous small‐vessel vasculitis associated with paediatric ulcerative colitis: A case study and literature review

“…). Using the keyword ‘ulcerative colitis’, 248 articles were found, of which 7 described the occurrence of LCV in the UC paediatric population . Using the keyword ‘Crohn's disease’, 266 papers were found.…”

“…All case reports concerning cutaneous lesions diagnosed as LCV at skin biopsy were included according to the EULAR/PRINTO/PRES classification criteria of childhood vasculitis . A summary of clinical features and treatment outcomes of 10 selected cases of LCV in paediatric patients with IBD is presented in Table . LCV occurs mostly in adolescents, with a striking female predominance of nearly 3:1.…”

“…The clinical response obtained in our case after the start of methotrexate shows that LCV can be considered an EIM of IBD. On the other hand, increasing evidence for anti‐tumour necrosis factor‐α agent efficacy in cutaneous EIMs exists …”

Leukocytoclastic vasculitis in an adolescent with ulcerative colitis: Report of a case and review of the literature

“…Synchronous presentation of LV and UC occurred in one patient (8%). 11–19 Of the reported patients, LV manifested during active colitis in six patients (50%) and in the absence of colitis in two patients (17%). The other four patients (33%) initially developed LV prior to any symptoms of UC, but all developed recurrent LV with subsequent onset of active colitis.…”

Vasculitis leucocitoclásticas como manifestación extraintestinal dermatológica rara de la enfermedad inflamatoria intestinal asociada con Clostridium: reporte de un caso

“…Su presentación clínica de vasculitis leucocitoclástica se caracteriza por púrpura palpable, con síntomas de dolor y ardor en múltiples áreas (58 %) o en un solo sitio (42 %). Sus lesiones se localizan predominantemente en las extremidades inferiores (83 %), seguidas de las extremidades superiores (42 %), el tronco (25 %) y los glúteos (25 %) (3,12,13). Ante la sospecha de vasculitis leucocitoclástica como manifestación extraintestinal dermatológica de CU, se debe realizar una biopsia cutánea para observar las características histológicas de infiltración de neutrófilos y linfocitos alrededor de los vasos sanguíneos dérmicos que muestran leucocitoclasia, depósito de fibrina en los vasos, trombos de fibrina, extravasación de eritrocitos y necrosis epidérmica resultante (10,14).…”

Cutaneous small‐vessel vasculitis associated with paediatric ulcerative colitis: A case study and literature review

“…). Using the keyword ‘ulcerative colitis’, 248 articles were found, of which 7 described the occurrence of LCV in the UC paediatric population . Using the keyword ‘Crohn's disease’, 266 papers were found.…”

“…All case reports concerning cutaneous lesions diagnosed as LCV at skin biopsy were included according to the EULAR/PRINTO/PRES classification criteria of childhood vasculitis . A summary of clinical features and treatment outcomes of 10 selected cases of LCV in paediatric patients with IBD is presented in Table . LCV occurs mostly in adolescents, with a striking female predominance of nearly 3:1.…”

“…The clinical response obtained in our case after the start of methotrexate shows that LCV can be considered an EIM of IBD. On the other hand, increasing evidence for anti‐tumour necrosis factor‐α agent efficacy in cutaneous EIMs exists …”